Epigenetic clocks that measure chronological or biological age are at present largely based on patterns of DNA methylation that change in characteristic ways over a lifetime. There are other options, such as looking at histones, but they are not as well explored. DNA methylation is the process or adding and removing methyl groups from nuclear DNA, changing its structure in ways that expose or hide gene sequences from the machinery of gene expression. These epigenetic decorations this control the production of proteins, and are continually changing in response to environmental factors a…
Physical Fitness Correlates with Slower Epigenetic Aging in Newer DNA Methylation Clocks
Epigenetic clocks that measure chronological or biological age are at present largely based on patterns of DNA methylation that change in characteristic ways over a lifetime. There are other options, such as looking at histones, but they are not as well explored. DNA methylation is the process or adding and removing methyl groups from nuclear DNA, changing its structure in ways that expose or hide gene sequences from the machinery of gene expression. These epigenetic decorations this control the production of proteins, and are continually changing in response to environmental factors a…