Planarians Undergo Rejuvenation When Regrowing Lost Tissues

Source https://www.fightaging.org/archives/2025/04/planarians-undergo-rejuvenation-when-regrowing-lost-tissues/

Some lower animal species are capable of exceptional feats of regeneration. Planarians are capable of regrowing an entire new body after being cut in half, for example. One way of thinking about this is that some of these species blur the line between developmental growth and regeneration. Adults make continued use of processes that occur during development, unlike most higher animals. One of the interesting aspects of early development is that adult germline cells undergo rejuvenation, shedding age-related changes in gene expression. Here, researchers show that adult planarians are in fact undergoing rejuvenation while they regrow lost body parts.

Long-lived species provide unique opportunities to uncover naturally evolved mechanisms f…

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