Source https://www.fightaging.org/archives/2023/04/reporting-on-the-immune-system-composition-of-centenarians/
Centenarians exhibit some different immune systems characteristics when compared against the general population in earlier old age. Whether this offers any meaningful degree of protection is an open question. Even if these differences are protective, one should expect that biochemical characteristics that are found to a greater degree in centenarians will only slightly improve the small odds of living to be this old in the context of the medical technology and lifestyle choices of the last century. It doesn’t take much of a change, say 1.25% survival odds rather than 1% survival odds, to see a lot more of that mechanism operating in the living population very old people, when compared to the population at large. That doesn’t make the underlying mechanism a desirable basis for an enhancement therapy – it is achieving far too little to be worth the time and effort.
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Source https://www.fightaging.org/archives/2023/04/reporting-on-the-immune-system-composition-of-centenarians/
Centenarians exhibit some different immune systems characteristics when compared against the general population in earlier old age. Whether this offers any meaningful degree of protection is an open question. Even if these differences are protective, one should expect that biochemical characteristics that are found to a greater degree in centenarians will only slightly improve the small odds of living to be this old in the context of the medical technology and lifestyle choices of the last century. It doesn’t take much of a change, say 1.25% survival odds rather than 1% survival odds, to see a lot more of that mechanism operating in the living population very old people, when compared to the population at large. That doesn’t make the underlying mechanism a desirable basis for an enhancement therapy – it is achieving far too little to be worth the time and effort.
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