Source https://www.fightaging.org/archives/2021/05/revisiting-the-end-of-the-disease-era/
The concept of a neatly packaged definition of a disease works well when dealing with the realm of infectious conditions. There is a pathogen, the pathogen causes certain symptoms, and one works towards intervention based on, for example, getting rid of the pathogen or interfering in its ability to do harm. Since medicine was largely concerned with tackling infectious disease until comparatively recently, the disease model has become very ingrained in the medical and regulatory community.
Unfortunately, this model doesn’t work well for age-related disease. The situation is completely different. Aging involves a network of interacting, layered, underlying processes of molecular damage and consequent tissue dysfunction. Senescent cells and <a href="https://www.fightaging.org/archives/2014/10/cr…
Source https://www.fightaging.org/archives/2021/05/revisiting-the-end-of-the-disease-era/
The concept of a neatly packaged definition of a disease works well when dealing with the realm of infectious conditions. There is a pathogen, the pathogen causes certain symptoms, and one works towards intervention based on, for example, getting rid of the pathogen or interfering in its ability to do harm. Since medicine was largely concerned with tackling infectious disease until comparatively recently, the disease model has become very ingrained in the medical and regulatory community.
Unfortunately, this model doesn’t work well for age-related disease. The situation is completely different. Aging involves a network of interacting, layered, underlying processes of molecular damage and consequent tissue dysfunction. Senescent cells and <a href="https://www.fightaging.org/archives/2014/10/cr…
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