This very interesting paper finds evidence of early adult impairment of cognitive function to correlate with Alzheimer’s-associated biomarkers such as tau and neurofilament light chain. It is well known that Alzheimer’s disease has a decades-long onset. Measurable biomarkers are associated with future pathology well in advance. Nonetheless, to extend that back to as early an age as mid-20s is a novel way of looking at the progression of cognitive decline over a lifetime. One has to wonder to what degree this is a measurement of the effects of poor lifestyle maintenance or exposure to persistent pathogens</…
Risk Factors for Alzheimer's Correlate with Impaired Cognition in Early Adult Life
This very interesting paper finds evidence of early adult impairment of cognitive function to correlate with Alzheimer’s-associated biomarkers such as tau and neurofilament light chain. It is well known that Alzheimer’s disease has a decades-long onset. Measurable biomarkers are associated with future pathology well in advance. Nonetheless, to extend that back to as early an age as mid-20s is a novel way of looking at the progression of cognitive decline over a lifetime. One has to wonder to what degree this is a measurement of the effects of poor lifestyle maintenance or exposure to persistent pathogens</…