A range of evidence points to degeneration of neuromuscular junctions as an important contribution to the characteristic loss of muscle mass and strength that takes place with age, leading to sarcopenia. Neuromuscular junctions are the structurally complex link between muscle fibers and the nervous system. While the fine details are not well understood at this time, it seems plausible that some downstream effect of neuromuscular junction activity is necessary for tissue maintenance in muscles to function correctly. When neuromuscular junctions suffer dysfunction due to the underlying molecular damage of aging, muscles suffer as wel…
Schwann Cells Contribute to Neuromuscular Junction Aging
A range of evidence points to degeneration of neuromuscular junctions as an important contribution to the characteristic loss of muscle mass and strength that takes place with age, leading to sarcopenia. Neuromuscular junctions are the structurally complex link between muscle fibers and the nervous system. While the fine details are not well understood at this time, it seems plausible that some downstream effect of neuromuscular junction activity is necessary for tissue maintenance in muscles to function correctly. When neuromuscular junctions suffer dysfunction due to the underlying molecular damage of aging, muscles suffer as wel…