Senescent Schwann Cells Impair Nerve Regeneration in Older Individuals

Source https://www.fightaging.org/archives/2023/11/senescent-schwann-cells-impair-nerve-regeneration-in-older-individuals/

Senescent cells of many types accumulate in tissues throughout the body with age due to an imbalance between the pace of creation and pace of destruction, the immune system progressively losing its ability to destroy these senescent cells in a timely manner. Senescent cells cease to replicate and secrete a potent mix of pro-inflammatory signals, harmful to surrounding tissue when sustained over the long term. Here, researchers note one of the many specific ways in which senescent cells can impair function; this one example is multiplied a thousand times across locations, tissue types, and cell types throughout the aging body.

Following peripheral nerve…

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