Degenerative disc disease is commonplace, and in recent years research has implicated the age-related accumulation of senescent cells in the onset and progression of this condition. Senolytic drugs to clear senescent cells may thus be a useful treatment. Existing senolytics, such as the dasatinib and quercetin combination, could be applied to many age-related conditions, since senescent cells and their inflammatory secretions produce broad negative e…
Senolytics as a Treatment for Intervertebral Disc Degeneration
Degenerative disc disease is commonplace, and in recent years research has implicated the age-related accumulation of senescent cells in the onset and progression of this condition. Senolytic drugs to clear senescent cells may thus be a useful treatment. Existing senolytics, such as the dasatinib and quercetin combination, could be applied to many age-related conditions, since senescent cells and their inflammatory secretions produce broad negative e…