Source https://www.fightaging.org/archives/2020/01/hypoxia-inducible-factors-in-vascular-aging/
Stress response mechanisms have been shown to be important in the way in which metabolism determines longevity in any given species. Short-lived species exhibit great plasticity of life span in response to stresses such as heat, cold, nutrient deprivation, and hypoxia. A mild or transient stress can trigger lasting upregulation of cell and tissue maintenance activities, leading to improved function and a slowed aging process. Most such stress responses converge on the processes of autophagy responsible for recycling unwanted or damaged protein machinery and cell structures.
One of numerous lines of inquiry in this part of the field of aging research is focused on hypoxia-induci…
Source https://www.fightaging.org/archives/2020/01/hypoxia-inducible-factors-in-vascular-aging/
Stress response mechanisms have been shown to be important in the way in which metabolism determines longevity in any given species. Short-lived species exhibit great plasticity of life span in response to stresses such as heat, cold, nutrient deprivation, and hypoxia. A mild or transient stress can trigger lasting upregulation of cell and tissue maintenance activities, leading to improved function and a slowed aging process. Most such stress responses converge on the processes of autophagy responsible for recycling unwanted or damaged protein machinery and cell structures.
One of numerous lines of inquiry in this part of the field of aging research is focused on hypoxia-induci…
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