A Discussion of Developmental Effects on Aging

Source https://www.fightaging.org/archives/2019/09/a-discussion-of-developmental-effects-on-aging/

To what degree does early life development impact the trajectory of late life aging? Plenty of evidence suggests a connection, much of it from epidemiological studies that, unfortunately, given little insight into possible mechanisms. Of other work, applying reliability theory to aging can only fit the observed mortality data if we are born with a non-zero level of damage. Further, early exposure to cytomegalovirus, a persistent infection that is corrosive of immune function over the long term, may explain links between socioeconomic status in childhood and pace of late life a…

Source https://www.fightaging.org/archives/2019/09/a-discussion-of-developmental-effects-on-aging/

To what degree does early life development impact the trajectory of late life aging? Plenty of evidence suggests a connection, much of it from epidemiological studies that, unfortunately, given little insight into possible mechanisms. Of other work, applying reliability theory to aging can only fit the observed mortality data if we are born with a non-zero level of damage. Further, early exposure to cytomegalovirus, a persistent infection that is corrosive of immune function over the long term, may explain links between socioeconomic status in childhood and pace of late life a…

You Can Have a Tender Heart and Still Be Fierce

Source http://feedproxy.google.com/~r/tinybuddha/~3/aM2kyW3_dJM/

“Life is a balance between what we can control and what we cannot. I am learning to live between effort and surrender.” ~Danielle Orner

For too long, I felt myself pulled between two shores of my identity. On one side was my yoga teacher, meditator, healer identity—my tender side. On the other side was my activist, change-maker role—my fierce side.

I always felt like I was too tender for some and too fierce for others. It made me feel like I didn’t fit in anywhere.

Definitely the soft-hearted “woo” person in my activist circles. And I was definitely the one talking about structural oppression and other activist ideas in my yoga teacher trainings. (The ahimsa lecture was always a sticky one.)

What I now know is that both of these sides of …

Source http://feedproxy.google.com/~r/tinybuddha/~3/aM2kyW3_dJM/

“Life is a balance between what we can control and what we cannot. I am learning to live between effort and surrender.” ~Danielle Orner

For too long, I felt myself pulled between two shores of my identity. On one side was my yoga teacher, meditator, healer identity—my tender side. On the other side was my activist, change-maker role—my fierce side.

I always felt like I was too tender for some and too fierce for others. It made me feel like I didn’t fit in anywhere.

Definitely the soft-hearted “woo” person in my activist circles. And I was definitely the one talking about structural oppression and other activist ideas in my yoga teacher trainings. (The ahimsa lecture was always a sticky one.)

What I now know is that both of these sides of …

Fight Aging! Newsletter, September 23rd 2019

Source https://www.fightaging.org/archives/2019/09/fight-aging-newsletter-september-23rd-2019/

Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/

Longevity Industry Consulting Services

Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/

Contents

  • Matthew O’Connor Presenting on Underdog Pharmaceuticals at Undoing Aging 2019
  • Arguing for Extracel…

Source https://www.fightaging.org/archives/2019/09/fight-aging-newsletter-september-23rd-2019/

Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/

Longevity Industry Consulting Services

Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/

Contents

  • Matthew O’Connor Presenting on Underdog Pharmaceuticals at Undoing Aging 2019
  • Arguing for Extracel…

Microtubule Function and Longevity in Nematodes

Source https://www.fightaging.org/archives/2019/09/microtubule-function-and-longevity-in-nematodes/

Researchers here report on genetic manipulations that alter the function of microtubules in the cells of nematode worms and thereby cause increased longevity. Microtubules help to support cell structure, and act as pathways to allow movement of structures and molecules around the cell. The effect on longevity appear to be mediated via improved or altered function of neurons, leading to alterations in metabolism of a sort already known to influence life span in this species. The degree to which this is relevant to aging in higher organisms remains to be established, but as a general rule one should expect ever smaller effect sizes for this sort of thing as one moves to test in larger and longer-lived species. Short-lived species have lifespans that are very plastic in response to metabolic stress and environmental change, wh…

Source https://www.fightaging.org/archives/2019/09/microtubule-function-and-longevity-in-nematodes/

Researchers here report on genetic manipulations that alter the function of microtubules in the cells of nematode worms and thereby cause increased longevity. Microtubules help to support cell structure, and act as pathways to allow movement of structures and molecules around the cell. The effect on longevity appear to be mediated via improved or altered function of neurons, leading to alterations in metabolism of a sort already known to influence life span in this species. The degree to which this is relevant to aging in higher organisms remains to be established, but as a general rule one should expect ever smaller effect sizes for this sort of thing as one moves to test in larger and longer-lived species. Short-lived species have lifespans that are very plastic in response to metabolic stress and environmental change, wh…

New Health Study Reveals Social Gamification + Competition Spurs Physical Activity Among Overweight and Obese Adults

Source https://www.clubindustry.com/news-central/new-health-study-reveals-social-gamification-competition-spurs-physical-activity-among

Club Industry was not involved in the creation of this content. 

New York, NY, September 2019 – According to new study findings published by JAMA Internal Medicine ( JAMANetwork.com), behavioral economics-based gamification led to “signifi…

Source https://www.clubindustry.com/news-central/new-health-study-reveals-social-gamification-competition-spurs-physical-activity-among

Club Industry was not involved in the creation of this content. 

New York, NY, September 2019 – According to new study findings published by JAMA Internal Medicine ( JAMANetwork.com), behavioral economics-based gamification led to “signifi…

Quantifying the Correlation Between Poverty and Faster Pace of Aging

Source https://www.fightaging.org/archives/2019/09/quantifying-the-correlation-between-poverty-and-faster-pace-of-aging/

It is well known that wealth correlates with greater life expectancy and related measures such as improved health in later life. The question has always been why this is the case. Wealth correlates with a range of other factors such as education, intelligence, and so forth, all of which can be reasonably expected to influence health via lifestyle choices. In the case of intelligence, there is also some evidence to suggest that more intelligent people are also …

Source https://www.fightaging.org/archives/2019/09/quantifying-the-correlation-between-poverty-and-faster-pace-of-aging/

It is well known that wealth correlates with greater life expectancy and related measures such as improved health in later life. The question has always been why this is the case. Wealth correlates with a range of other factors such as education, intelligence, and so forth, all of which can be reasonably expected to influence health via lifestyle choices. In the case of intelligence, there is also some evidence to suggest that more intelligent people are also …

PLAE Expands High-Performance Equipment and Flooring Solutions

Source https://www.clubindustry.com/news-central/plae-expands-high-performance-equipment-and-flooring-solutions

Club Industry was not involved in the creation of this content. 

WOODSTOCK, Ga. – Sept. 18, 2019 – Since its beginning, PLAE has been known globally for innovating premium solutions for customers that demand the best. The company now is adding…

Source https://www.clubindustry.com/news-central/plae-expands-high-performance-equipment-and-flooring-solutions

Club Industry was not involved in the creation of this content. 

WOODSTOCK, Ga. – Sept. 18, 2019 – Since its beginning, PLAE has been known globally for innovating premium solutions for customers that demand the best. The company now is adding…

Mountainside Fitness to Honor Active Duty Military Members & Veterans by Awarding 5 Free Lifelong Memberships

Source https://www.clubindustry.com/news-central/mountainside-fitness-honor-active-duty-military-members-veterans-awarding-5-free

Club Industry was not involved in the creation of this content.

(PHOENIX) —  Military veterans and current active duty military members can be awarded free lifelong memberships at Mountainside Fitness.

Mountainside Fitness is honorin…

Source https://www.clubindustry.com/news-central/mountainside-fitness-honor-active-duty-military-members-veterans-awarding-5-free

Club Industry was not involved in the creation of this content.

(PHOENIX) —  Military veterans and current active duty military members can be awarded free lifelong memberships at Mountainside Fitness.

Mountainside Fitness is honorin…

Reviewing the Aging of Lymphatic Vessels

Source https://www.fightaging.org/archives/2019/09/reviewing-the-aging-of-lymphatic-vessels/

The lymphatic system a part of the broader circulatory system and has many similarities to the cardiovascular system of blood vessels. The lymphatic system is also a network of vessels, transporting various necessary cells and substances, and subject to processes of aging that degrade function and thereby cause issues. While circulation of fluid is an important function of the lymphatic system, and conditions such as lymphedema arise when it runs awry, the role of lymphatic vessels in the function of the immune system is arguably far more vital.

Immune cells must be able to rapidly travel the body and locally coordinate with one another in order to mount an effective i…

Source https://www.fightaging.org/archives/2019/09/reviewing-the-aging-of-lymphatic-vessels/

The lymphatic system a part of the broader circulatory system and has many similarities to the cardiovascular system of blood vessels. The lymphatic system is also a network of vessels, transporting various necessary cells and substances, and subject to processes of aging that degrade function and thereby cause issues. While circulation of fluid is an important function of the lymphatic system, and conditions such as lymphedema arise when it runs awry, the role of lymphatic vessels in the function of the immune system is arguably far more vital.

Immune cells must be able to rapidly travel the body and locally coordinate with one another in order to mount an effective i…