Immunosenescence is the age-related incapacity of the immune system, while inflammaging is the age-related overactivity of the immune system, overreacting to signals of damage in the body. Both are disruptive to tissue function, health, and odds of survival in later life. They are flip sides of the same coin, labels for emergent properties of the combined interactions of many forms of damage and dysfunction that accumulate with age. The decline of the immune system is clearly important in the onset and progression of many age-related conditions; more resources should be devoted to approaches capable of immune rejuvenation, such as <a href="htt…
The Relationship Between Immunosenescence and Inflammaging
Immunosenescence is the age-related incapacity of the immune system, while inflammaging is the age-related overactivity of the immune system, overreacting to signals of damage in the body. Both are disruptive to tissue function, health, and odds of survival in later life. They are flip sides of the same coin, labels for emergent properties of the combined interactions of many forms of damage and dysfunction that accumulate with age. The decline of the immune system is clearly important in the onset and progression of many age-related conditions; more resources should be devoted to approaches capable of immune rejuvenation, such as <a href="htt…