Autophagy in the Context of Immune System Aging

Source https://www.fightaging.org/archives/2022/02/autophagy-in-the-context-of-immune-system-aging/

Autophagy is the name given to a collection of cellular maintenance processes that identify and break down worn and unwanted proteins and structures in the cell. More efficient autophagy in principle produces better cell and tissue function, and, over the long term, slower aging. A sizable portion of the research community is interested in autophagy in the context of aging, but outside the development of calorie restriction mimetic drugs, few groups are working towards therapies intended to upregulate autophagy in a targeted fashion. A program in the Life Biosciences portfolio is one of the limited number of examples.

The ability of calorie restriction to lengthen healthy life in short-lived species is largely…

Source https://www.fightaging.org/archives/2022/02/autophagy-in-the-context-of-immune-system-aging/

Autophagy is the name given to a collection of cellular maintenance processes that identify and break down worn and unwanted proteins and structures in the cell. More efficient autophagy in principle produces better cell and tissue function, and, over the long term, slower aging. A sizable portion of the research community is interested in autophagy in the context of aging, but outside the development of calorie restriction mimetic drugs, few groups are working towards therapies intended to upregulate autophagy in a targeted fashion. A program in the Life Biosciences portfolio is one of the limited number of examples.

The ability of calorie restriction to lengthen healthy life in short-lived species is largely…

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