Further Evidence for Cellular Senescence to Contribute to Atrial Fibrillation

Source https://www.fightaging.org/archives/2022/02/further-evidence-for-cellular-senescence-to-contribute-to-atrial-fibrillation/

Senescent cells accumulate with age, and their secretions provoke chronic inflammation and tissue dysfunction. With this in mind, researchers have shown that cellular senescence correlates with atrial fibrillation in older people. Here is a more recent demonstration of this relationship. I’m not aware of a study that shows senolytic therapy to remove senescent cells is a useful treatment for atrial fibrillation, but evaluation of this approach seems a good idea, both in aged animal models and in human patients.

Atrial fibrillation (…

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