Elastin Fragmentation and the Elastin Receptor Complex in Aging Blood Vessels

Source https://www.fightaging.org/archives/2022/03/elastin-fragmentation-and-the-elastin-receptor-complex-in-aging-blood-vessels/

Elastin is a vital component of the complex structure of the extracellular matrix in flexible, elastic tissues, such as skin and blood vessel walls. It is the extracellular matrix that determines physical tissue properties, such as strength, elasticity, and so forth. This structure becomes disarrayed with age for a variety of reasons: photoaging that breaks down molecules or encourages alterations; cross-linking between molecules that restricts their range of motion; changes in the behavior of cells that maintain the structure.

Today’s open access paper looks at a different aspect of this issue. The researchers discuss what happens to the debris from elastin that is broken down, and how …

Source https://www.fightaging.org/archives/2022/03/elastin-fragmentation-and-the-elastin-receptor-complex-in-aging-blood-vessels/

Elastin is a vital component of the complex structure of the extracellular matrix in flexible, elastic tissues, such as skin and blood vessel walls. It is the extracellular matrix that determines physical tissue properties, such as strength, elasticity, and so forth. This structure becomes disarrayed with age for a variety of reasons: photoaging that breaks down molecules or encourages alterations; cross-linking between molecules that restricts their range of motion; changes in the behavior of cells that maintain the structure.

Today’s open access paper looks at a different aspect of this issue. The researchers discuss what happens to the debris from elastin that is broken down, and how …

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