The Role of Mitochondrial DNA Mutation in Aging Remains Much Debated

Source https://www.fightaging.org/archives/2022/03/the-role-of-mitochondrial-dna-mutation-in-aging-remains-much-debated/

Mitochondria are the power plants of the cell, deeply integrated into many core cellular processes, but most importantly, responsible for generating the energy store molecule adenosine triphosphate (ATP), used to power cellular processes. Mitochondria are descended from ancient symbiotic bacteria, and act like bacteria in many ways, fusing and dividing, and passing around component parts promiscuously. Every cell contains a herd of hundreds of these organelles, monitored by quality control processes that destroy worn mitochondria in order to maintain overall function.

Importantly, mitochondria contain their own small circular genome. Mitochondrial DNA is less well protected than t…

Source https://www.fightaging.org/archives/2022/03/the-role-of-mitochondrial-dna-mutation-in-aging-remains-much-debated/

Mitochondria are the power plants of the cell, deeply integrated into many core cellular processes, but most importantly, responsible for generating the energy store molecule adenosine triphosphate (ATP), used to power cellular processes. Mitochondria are descended from ancient symbiotic bacteria, and act like bacteria in many ways, fusing and dividing, and passing around component parts promiscuously. Every cell contains a herd of hundreds of these organelles, monitored by quality control processes that destroy worn mitochondria in order to maintain overall function.

Importantly, mitochondria contain their own small circular genome. Mitochondrial DNA is less well protected than t…

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