Source https://www.fightaging.org/archives/2022/07/efficient-epigenetic-clocks-may-not-be-useful-epigenetic-clocks/
An epigenetic clock is a weighted algorithmic combination of the methylation status of various specific CpG sites on the genome, where the number produced matches well with chronological or biological age. It is constructed by applying machine learning techniques to epigenetic data, a catalogue of DNA methylation patterns across the full structure of the genome, taken from blood samples of mice or people at various ages. The early epigenetic clocks use hundreds of CpG sites, and therefore one might reasonably hypothesize that they reflect the entire breadth of the processes of aging. That turns out not to be true, but it was reasonable.
As work on the production of epigenetic clocks prog…
Source https://www.fightaging.org/archives/2022/07/efficient-epigenetic-clocks-may-not-be-useful-epigenetic-clocks/
An epigenetic clock is a weighted algorithmic combination of the methylation status of various specific CpG sites on the genome, where the number produced matches well with chronological or biological age. It is constructed by applying machine learning techniques to epigenetic data, a catalogue of DNA methylation patterns across the full structure of the genome, taken from blood samples of mice or people at various ages. The early epigenetic clocks use hundreds of CpG sites, and therefore one might reasonably hypothesize that they reflect the entire breadth of the processes of aging. That turns out not to be true, but it was reasonable.
As work on the production of epigenetic clocks prog…
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