Correlating Epigenetic Age Acceleration with Survival in Older Individuals

Source https://www.fightaging.org/archives/2022/08/correlating-epigenetic-age-acceleration-with-survival-in-older-individuals/

An epigenetic clock produces an epigenetic age from a patient blood or tissue sample. These clocks are trained on data from many individuals at varying ages. When the measured epigenetic age is greater than chronological age, in other words that their biochemistry looks more like that of older people from the training data, this is referred to as epigenetic age acceleration, and is thought to represent a more rapid progression of degenerative aging. Numerous studies have correlated epigenetic age acceleration with risk of specific age-related conditions. Here, researchers correlate it with odds of survival to late life. The worse the epigenetic age acceleration, the worse the odds of survival.

To our knowledge, this cohort study is the first study examining the association between epi…

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