P2Y6R Inhibition as a Strategy to Reduce Age-Related Memory Loss

Source https://www.fightaging.org/archives/2023/01/p2y6r-inhibition-as-a-strategy-to-reduce-age-related-memory-loss/

Memory is in some way encoded in the synaptic connections between neurons, with the precise details yet to be determined. Destruction of synapses is a characteristic of neurodegenerative conditions involving loss of memory. Researchers here identify a regulatory receptor that controls the removal of synapses by the innate immune cells known as microglia in the brains of mice. Blocking the activity of this receptor reduces age-related memory loss in mice, suggesting that this aspect of aging is largely a matter of inappropriate microglial activity, destroying synapses that should remain intact.

Removal of synapses is not …

Source https://www.fightaging.org/archives/2023/01/p2y6r-inhibition-as-a-strategy-to-reduce-age-related-memory-loss/

Memory is in some way encoded in the synaptic connections between neurons, with the precise details yet to be determined. Destruction of synapses is a characteristic of neurodegenerative conditions involving loss of memory. Researchers here identify a regulatory receptor that controls the removal of synapses by the innate immune cells known as microglia in the brains of mice. Blocking the activity of this receptor reduces age-related memory loss in mice, suggesting that this aspect of aging is largely a matter of inappropriate microglial activity, destroying synapses that should remain intact.

Removal of synapses is not …

What Do You Think?

comments

Translate »