Source https://www.fightaging.org/archives/2023/01/a-view-of-cellular-senescence-in-cancer/
Cellular senescence is a double-edged sword in the matter of cancer. A cancer cell turned senescent, and thus entered a state of growth arrest, is not a cancer cell that continues to replicate. It secretes pro-growth, pro-inflammatory signals that draw the attention of the immune system. This can be beneficial, helping to defeat a cancer, particularly in the early stages. After a certain point, however, too much cellular senescence aids the cancer in further growth. While it seems clear that senolytic treatments to remove lingering senescent cells…
Source https://www.fightaging.org/archives/2023/01/a-view-of-cellular-senescence-in-cancer/
Cellular senescence is a double-edged sword in the matter of cancer. A cancer cell turned senescent, and thus entered a state of growth arrest, is not a cancer cell that continues to replicate. It secretes pro-growth, pro-inflammatory signals that draw the attention of the immune system. This can be beneficial, helping to defeat a cancer, particularly in the early stages. After a certain point, however, too much cellular senescence aids the cancer in further growth. While it seems clear that senolytic treatments to remove lingering senescent cells…
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