The Genetic Basis for Aging: Much Data, Few Conclusions

Source https://www.fightaging.org/archives/2023/01/the-genetic-basis-for-aging-much-data-few-conclusions/

As this paper notes, there is a great deal of data regarding genetics and aging, but as yet little in the way of useful conclusions when it comes to applying this knowledge to extend the healthy human life span. From a reductionist point of view, it is clear that genetic differences lie at the root of the large differences in trajectory of aging and life span that are observed between species. The evidence to date suggests that genetic variance within a species has little impact on life span, however. The observe range of life expectancy within a species is mostly a matter of environment and lifestyle. A great deal of funding and effort goes into the continued investigation of the genetics of human longevity, but it isn’t at all clear that this will lead to ways to meaningfully extend healthy life span.

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