Blarcamesine Slows Progression of Alzheimer's Disease in a Human Trial

Source https://www.fightaging.org/archives/2023/09/blarcamesine-slows-progression-of-alzheimers-disease-in-a-human-trial/

Is maladaptive loss of autophagy a meaningful contributing factor in Alzheimer’s disease? The results of a recent clinical trial suggest so. Autophagy is the name given to a collection of cellular maintenance processes responsible for recycling unwanted proteins, molecular waste, and damaged cell components. Improving autophagy should in turn improve cell function. The drug development program noted here has reached the stage of later human trials to assess efficacy, and is focused on correcting one specific mechanism that appears to negatively affect autophagy in the Alzheimer’s brain, and that in turn helps to clear out damaging protein aggregates associated with Alzheimer’s disease pathology.

Blarcamesine works by sele…

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