A Mismatch Between Central versus Peripheral Circadian Regulation in Aging

Source https://www.fightaging.org/archives/2024/05/a-mismatch-between-central-versus-peripheral-circadian-regulation-in-aging/

Researchers here present an interesting view of age-related circadian dysfunction, focusing on mismatched regulation between the central circadian clock and somewhat independent peripheral clocks. The regulation of circadian rhythm in tissues results from the activities of these complex systems of multiple parts – and like all complex systems they begin to exhibit dysfunction with advancing age. The novel aspect of this research is the concept of multiple mismatched circadian regulators as a cause of further dysfunction in tissues.

Discovered in the 1970s, circadian clocks are essential for the regulation of biological time in most cells in the human body. These internal mechanisms adjust biological processe…

Source https://www.fightaging.org/archives/2024/05/a-mismatch-between-central-versus-peripheral-circadian-regulation-in-aging/

Researchers here present an interesting view of age-related circadian dysfunction, focusing on mismatched regulation between the central circadian clock and somewhat independent peripheral clocks. The regulation of circadian rhythm in tissues results from the activities of these complex systems of multiple parts – and like all complex systems they begin to exhibit dysfunction with advancing age. The novel aspect of this research is the concept of multiple mismatched circadian regulators as a cause of further dysfunction in tissues.

Discovered in the 1970s, circadian clocks are essential for the regulation of biological time in most cells in the human body. These internal mechanisms adjust biological processe…

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