T cell senescence is a noted feature of the aging immune system. T cells mature in the thymus, which atrophies with age. Absent a supply of new T cells, the existing populations are forced into greater cellular replication in order to (a) maintain a steady number of cells, and (b) continue to respond to infection with an expansion of the number of T cells equipped to attack the pathogen. Cellular senescence occurs when a cell reaches the Hayflick limit to replication. With each cell division, <a href="https://en.wikipedia.org/wiki/Tel…
Senescent T Cells Contribute to Neurodegenerative Conditions
T cell senescence is a noted feature of the aging immune system. T cells mature in the thymus, which atrophies with age. Absent a supply of new T cells, the existing populations are forced into greater cellular replication in order to (a) maintain a steady number of cells, and (b) continue to respond to infection with an expansion of the number of T cells equipped to attack the pathogen. Cellular senescence occurs when a cell reaches the Hayflick limit to replication. With each cell division, <a href="https://en.wikipedia.org/wiki/Tel…