This research makes for interesting reading in the context of a recent paper discussing a mismatch between brain and body circadian clocks as a contributing factor to degenerative aging. Researchers here show that an accumulation of senescent cells in the adrenal gland disrupts its adherence to circadian rhythm, while targeted removal of those cells restores function. We might add this to the many good reasons to remove lingering senescent cells from the aging body. These cells secrete a potent mix of pro-inflammatory factors that are disruptive to …
Cellular Senescence Disrupts Adrenal Gland Circadian Rhythm in Aging Mice
This research makes for interesting reading in the context of a recent paper discussing a mismatch between brain and body circadian clocks as a contributing factor to degenerative aging. Researchers here show that an accumulation of senescent cells in the adrenal gland disrupts its adherence to circadian rhythm, while targeted removal of those cells restores function. We might add this to the many good reasons to remove lingering senescent cells from the aging body. These cells secrete a potent mix of pro-inflammatory factors that are disruptive to …