Centenarians Exhibit a Higher Expression of Metallothioneins in Astrocytes

Source https://www.fightaging.org/archives/2024/05/centenarians-exhibit-a-higher-expression-of-metallothioneins-in-astrocytes/

A considerable amount of effort has gone into assessing the biochemical differences between old people and extremely old people, in search of protective mechanisms that might be used as a basis for therapies to modestly slow the pace of aging. This may not be the best approach from the point of view of size of effect achieved at the end of the day, as centenarians are still meaningfully impacted by aging, their physiology far removed from that of a young individual, but it is an approach well suited to the present environment of low cost omics technologies. Everything that can be measured attracts attention, and the cheaper the measure is to enact, the more that researchers will use it.

Previous studies of the aging human brain have shown dynamic gene expression changes that distinguish…

What Do You Think?

comments