Low Dose Naltrexone Produces a Small Extension of Life in Nematodes

Source https://www.fightaging.org/archives/2024/06/low-dose-naltrexone-produces-a-small-extension-of-life-in-nematodes/

Over the past decade, researchers have put a great deal of effort into automating and otherwise reducing the costs of studies of aging in nematode worms. A properly equipped team can now screen thousands of compounds in a year in nematodes, while obtaining good data on life span and pace of decline with age via a range of metrics. Sadly, short-lived species such as nematodes have life spans that are far more plastic in response to interventions than is the case for longer-lived species such as our own. A 10-20% increase in nematode life span is likely irrelevant to humans; some interventions that probably do little in humans have increased nematode life span by 100% or more. It is worth bearing this in mind when reading papers such as the one noted here.

There is increasing interest in the concept of aging as a <a href="https://en.wikipedia.or…

What Do You Think?

comments