Source https://www.fightaging.org/archives/2024/06/xbp1-upregulation-extends-life-in-flies/
The fly transcription factor xbp1 has been connected to improved cell maintenance resulting from calorie restriction and similar interventions. Researchers here dig into some of the biochemistry, finding that xbp1 upregulation produces different positive effects in different tissues, but overall acts to modestly slow aging and extend life span. This research is characteristic of the sort of exploration of biochemistry that results from studies of calorie restriction, as the changes produced in cell function are extensive. There is a great deal of ground to cover and only so many researchers. We might expect a full understanding of the response …
Source https://www.fightaging.org/archives/2024/06/xbp1-upregulation-extends-life-in-flies/
The fly transcription factor xbp1 has been connected to improved cell maintenance resulting from calorie restriction and similar interventions. Researchers here dig into some of the biochemistry, finding that xbp1 upregulation produces different positive effects in different tissues, but overall acts to modestly slow aging and extend life span. This research is characteristic of the sort of exploration of biochemistry that results from studies of calorie restriction, as the changes produced in cell function are extensive. There is a great deal of ground to cover and only so many researchers. We might expect a full understanding of the response …
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