Blocking cGAS-STING Inflammatory Signaling Protects the Retina for Glaucoma

Source https://www.fightaging.org/archives/2024/06/blocking-cgas-sting-inflammatory-signaling-protects-the-retina-for-glaucoma/

Researchers here provide evidence for retinal degeneration to be driven in part by maladaptive innate immune signaling running through the cGAS-STING pathway. This pathway is the target of a fair amount of research these days, as the research community is interested in finding novel ways to effectively interfere in the chronic inflammation that is characteristic of aging and many forms of degenerative disease. As always seems to be the case, the challenge is that unwanted, harmful inflammatory signaling uses the same mechanisms as the desirable, short-term inflammatory signaling that is necessary to the function of the <a href="https://en.wikipedia….

Source https://www.fightaging.org/archives/2024/06/blocking-cgas-sting-inflammatory-signaling-protects-the-retina-for-glaucoma/

Researchers here provide evidence for retinal degeneration to be driven in part by maladaptive innate immune signaling running through the cGAS-STING pathway. This pathway is the target of a fair amount of research these days, as the research community is interested in finding novel ways to effectively interfere in the chronic inflammation that is characteristic of aging and many forms of degenerative disease. As always seems to be the case, the challenge is that unwanted, harmful inflammatory signaling uses the same mechanisms as the desirable, short-term inflammatory signaling that is necessary to the function of the <a href="https://en.wikipedia….

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