Low Dose Antifibrotic Drugs Slow Ovarian Aging in Mice

Source https://www.fightaging.org/archives/2024/07/low-dose-antifibrotic-drugs-slow-ovarian-aging-in-mice/

As in a number of other organs, fibrosis is a feature of the aging and loss of function of the ovaries. Fibrosis is the inappropriate deposition of excess collagen to the extracellular matrix, creating scar-like structures that are disruptive to normal tissue function. Here, researchers show that delivery of low dose antifibrotic drugs in mice can slow this aspect of ovarian aging and lead to improved function and extended reproductive longevity.

The female reproductive system is one of the first to age in humans, resulting in infertility and endocrine disruptions. The aging ovary assumes a fibro-inflamm…

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