Immunopeptide PEPITEM can Reduce Chronic Inflammatory Reactions in Old Mice

Source https://www.fightaging.org/archives/2024/07/immunopeptide-pepitem-can-reduce-chronic-inflammatory-reactions-in-old-mice/

Researchers here describe an injected immunomodulatory peptide that reduces migration of adaptive immune cells in response to inflammatory signaling. They mount the argument that excessive immune cell migration is a sizable part of the problem in the chronic inflammation of aging, and arises due to age-related changes in immune cell behavior. Delivering the peptide is intended to restore a more youthful regulation of this immune cell behavior.

Growing evidence suggests that the ageing process significantly impacts leukocyte trafficking dynamics during inflammation, thereby compromising protective immunity. …

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