Calorie Restriction Improves Beta Cell Function and Slows Beta Cell Aging

Source https://www.fightaging.org/archives/2024/11/calorie-restriction-improves-beta-cell-function-and-slows-beta-cell-aging/

The practice of calorie restriction alters near all aspects of cellular biochemistry throughout the body. The result is improved function and modestly slowed aging, an evolved response to low nutrient levels that serves to increase the odds of surviving a famine to reproduce once plenty returns. Seasonal famine is the most common such circumstance, and while the calorie restriction response appears to be near universal across all forms of life, short-lived species exhibit a much greater extension of life span as a result than is the case for long-lived species. A season is a sizable fraction of a mouse life span, but not of a human life span. So mice can live up to 40% longer on a low calorie diet, while humans likely gain only a few years.

Since calorie restriction changes just about everything for the better in the aging b…

Source https://www.fightaging.org/archives/2024/11/calorie-restriction-improves-beta-cell-function-and-slows-beta-cell-aging/

The practice of calorie restriction alters near all aspects of cellular biochemistry throughout the body. The result is improved function and modestly slowed aging, an evolved response to low nutrient levels that serves to increase the odds of surviving a famine to reproduce once plenty returns. Seasonal famine is the most common such circumstance, and while the calorie restriction response appears to be near universal across all forms of life, short-lived species exhibit a much greater extension of life span as a result than is the case for long-lived species. A season is a sizable fraction of a mouse life span, but not of a human life span. So mice can live up to 40% longer on a low calorie diet, while humans likely gain only a few years.

Since calorie restriction changes just about everything for the better in the aging b…

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