Neurodegenerative conditions are clearly associated with the chronic inflammation of aging. Unresolved inflammatory signaling is harmful to tissue structure and function, and a broad range of evidence points to dysregulated immune cell function in the brain as an important contribution to pathology. Inflammatory signaling is complex, however, and finding ways to intervene in unwanted sustained inflammatory reactions that do not also sabotage normal necessary short-term inflammatory reactions has so far proven to be challenging. Here, researchers focused on a well-studied innate immune regulator of inflammation, <a href="https:/…
A Role for STING Mediated Inflammation in Neurodegenerative Conditions
Neurodegenerative conditions are clearly associated with the chronic inflammation of aging. Unresolved inflammatory signaling is harmful to tissue structure and function, and a broad range of evidence points to dysregulated immune cell function in the brain as an important contribution to pathology. Inflammatory signaling is complex, however, and finding ways to intervene in unwanted sustained inflammatory reactions that do not also sabotage normal necessary short-term inflammatory reactions has so far proven to be challenging. Here, researchers focused on a well-studied innate immune regulator of inflammation, <a href="https:/…