Source https://www.fightaging.org/archives/2025/06/rna-splicing-dysfunction-in-the-aging-ovaries/
Genes consist of exon sequences and intron sequences that, once transcribed into RNA, are spliced together to form the final RNA molecule. Exons are usually included and introns usually excluded, but many genes can encode for multiple different RNA molecules via alternative splicing arrangements. The regulation of RNA splicing is complex, and like all complex aspects of our biochemistry it becomes dysfunctional with advancing age. The proportions of normal versus alternative splicing are altered, and outright incorrect RNA molecules can be formed as well.
It remains an open question as to the degree to which RNA splicing dysfunction is …
Source https://www.fightaging.org/archives/2025/06/rna-splicing-dysfunction-in-the-aging-ovaries/
Genes consist of exon sequences and intron sequences that, once transcribed into RNA, are spliced together to form the final RNA molecule. Exons are usually included and introns usually excluded, but many genes can encode for multiple different RNA molecules via alternative splicing arrangements. The regulation of RNA splicing is complex, and like all complex aspects of our biochemistry it becomes dysfunctional with advancing age. The proportions of normal versus alternative splicing are altered, and outright incorrect RNA molecules can be formed as well.
It remains an open question as to the degree to which RNA splicing dysfunction is …
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