Gene Therapy Reduces Ocular Pressure in a Mouse Model of Glaucoma

Source https://www.fightaging.org/archives/2025/06/gene-therapy-reduces-ocular-pressure-in-a-mouse-model-of-glaucoma/

The progressive blindness of glaucoma arises from pressure damage to the retina, the proximate cause being the presence of too much aqueous humor in the eye. The underlying causes are more complex and less well understood. As is the case for raised blood pressure, however, there are any number of ways to influence relevant mechanisms in order to control pressure without actually addressing the root cause damage and dysfunction of aging. Here, for example, researchers interfere in the expression of proteins critical in the production of aqueous humor, resulting in reduced pressure in the eye.

Glaucoma is a major global cause of irreversible vision loss. It is marked by eleva…

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