T Cell Reactivity as an Early Marker of Parkinson's Disease

Source https://www.fightaging.org/archives/2025/06/t-cell-reactivity-as-an-early-marker-of-parkinsons-disease/

The protein α-synuclein misfolds and spreads from neuron to neuron in the nervous system to cause the pathology of Parkinson’s disease. In Parkinson’s patients, it has been found that T cells exhibit increased reactivity to α-synuclein. That may contribute to inflammation and disease progression, but here researchers show that this reactivity exists and is measurable before evident symptoms of Parkinson’s disease emerge. Thus it may serve as the basis for a blood test to detect Parkinson’s in its earliest stages.

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