ARPA-H Launches Program to Develop Replacement Brain Tissue

Source https://www.fightaging.org/archives/2025/07/arpa-h-launches-program-to-develop-replacement-brain-tissue/

Studies of forms of brain cancer and other slow, progressive damage to specific regions of the brain have demonstrated that the information stored in at least some parts of the brain can move around. Undamaged parts of the brain can be repurposed in response to damage. This means that it is in principle possible to place new, functional tissue into some portions of the living brain and expect that tissue to become used and useful over time, a replacement for damaged tissue. Researchers are initially focused on the neocortex, one of the most plastic areas of the brain. The biggest challenge is to be able to engineer suitable neocortical tissue for transplantation, growing it from a patient’s own cells.

The Advanced Research Projects Agency for Health (ARPA-H), an agency within the U.S. Department of Health and Human Services (HHS),…

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