Mechanisms Involved in the Acceleration of Aging via Persistent Infection

Source https://www.fightaging.org/archives/2025/08/mechanisms-involved-in-the-acceleration-of-aging-via-persistent-infection/

Persistent infection via HIV, herpesvirus, or a range of other pathogens capable of evading or subverting the immune system might reasonably be thought of as producing accelerated aging. The dysfunction produced by these infections usually centers around the immune system, but this in turn negatively affects the function of tissues and systems throughout the body. Aging is an accumulation of damage, and persistent infection produces forms of damage that overlap with those generated during the normal course of aging. Here, researchers discuss the range of mechanisms thought to be involved.

Many models of aging assume that processes such as <a href="https://en.wikipedia.org/wiki…

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