Even in this age of single cell sequencing, a great deal of the categorization and counting of cells is still accomplished via assessment of cell surface proteins. The ability to cheaply create and manufacture novel antibodies that selectively bind to specific proteins naturally led to technologies such as flow cytometry that can separate and count cells that express a specific surface protein, or high versus low levels of that surface protein. The large number of proteins with names that start with “CD” for cluster of differentiation are so named because researchers have spent a lot of time looking for ways to distinguish different populations of <a href="https://en.wikipedia…
CD57 as a Marker of Immunological Aging, but Not Immune Cell Senescence
Even in this age of single cell sequencing, a great deal of the categorization and counting of cells is still accomplished via assessment of cell surface proteins. The ability to cheaply create and manufacture novel antibodies that selectively bind to specific proteins naturally led to technologies such as flow cytometry that can separate and count cells that express a specific surface protein, or high versus low levels of that surface protein. The large number of proteins with names that start with “CD” for cluster of differentiation are so named because researchers have spent a lot of time looking for ways to distinguish different populations of <a href="https://en.wikipedia…