It is never too late to start
Source https://www.theminimalists.com/autumn/
The Minimalists discuss seven items to consider decluttering this autumn—or any time of year.
What do you do to prepare for fall? Let us know in the YouTube comments.
The post 7 Things Pro Organizers Say You Should Declutter This Fall appeared first on The Minimalists.
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Source https://www.theminimalists.com/autumn/
The Minimalists discuss seven items to consider decluttering this autumn—or any time of year.
What do you do to prepare for fall? Let us know in the YouTube comments.
The post 7 Things Pro Organizers Say You Should Declutter This Fall appeared first on The Minimalists.
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Source https://www.fightaging.org/archives/2025/10/reviewing-the-aging-of-the-liver/
The liver is perhaps the most regenerative organ in the body, but like all other organs it is negatively affected by the accumulation of cell and tissue damage characteristic of aging. Liver function is reduced, while prevalent liver diseases such as metabolic dysfunction-associated steatoheptatitis occur more readily in older people than in younger people. With this in mind, researchers here present a tour of vulnerabilities to disease and dysfunction that are induced by mechanisms of aging in the liver.
While the liver can maintain some of its homeostatic functions throughout aging, it becomes highly susceptible to liver injury and chronic liver disease. This s…
Source https://www.fightaging.org/archives/2025/10/reviewing-the-aging-of-the-liver/
The liver is perhaps the most regenerative organ in the body, but like all other organs it is negatively affected by the accumulation of cell and tissue damage characteristic of aging. Liver function is reduced, while prevalent liver diseases such as metabolic dysfunction-associated steatoheptatitis occur more readily in older people than in younger people. With this in mind, researchers here present a tour of vulnerabilities to disease and dysfunction that are induced by mechanisms of aging in the liver.
While the liver can maintain some of its homeostatic functions throughout aging, it becomes highly susceptible to liver injury and chronic liver disease. This s…
When examining human epidemiological data, a web of correlations link health, life span, education, wealth, intelligence, and socioeconomic status. One can hypothesize about why these correlations exist, and to what degree different mechanisms contribute to the overall effect, but it remains challenging to draw firm conclusions from the data. For example, reasonably compelling evidence suggests t…
When examining human epidemiological data, a web of correlations link health, life span, education, wealth, intelligence, and socioeconomic status. One can hypothesize about why these correlations exist, and to what degree different mechanisms contribute to the overall effect, but it remains challenging to draw firm conclusions from the data. For example, reasonably compelling evidence suggests t…
Gene therapies for neurodegenerative diseases that involve direct injection into portions of the brain have become acceptable enough to regulators that there is now progress towards the clinic on this front. This is despite the invasive nature of the delivery, and despite the high bar for safety that that tends to be applied to treatments that produce permanent changes in a patient. One might look at a recent trial for Huntington’s disease, for example. This willingness on the part of regulators to allow more adventurous approaches might reflect a growing frustration with the failure to generate curative (or even meaningfully preventative) therapies for prevalent neurodegenerative conditions, after decades of significant funding and effort.
Another example at an earlier stage of development is the repro…
Gene therapies for neurodegenerative diseases that involve direct injection into portions of the brain have become acceptable enough to regulators that there is now progress towards the clinic on this front. This is despite the invasive nature of the delivery, and despite the high bar for safety that that tends to be applied to treatments that produce permanent changes in a patient. One might look at a recent trial for Huntington’s disease, for example. This willingness on the part of regulators to allow more adventurous approaches might reflect a growing frustration with the failure to generate curative (or even meaningfully preventative) therapies for prevalent neurodegenerative conditions, after decades of significant funding and effort.
Another example at an earlier stage of development is the repro…
Source https://tinybuddha.com/blog/why-you-cant-relax-and-how-to-let-yourself-rest/
“Rest and be thankful.” ~William Wordsworth
A few years ago, I caught myself doing something that made no sense.
It was late evening, my kids were asleep, the house finally quiet. I’d been counting down to this moment all day—dreaming of sinking into the couch, wrapping myself in a blanket, maybe even reading a book without distractions.
But when I lay down and closed my eyes, something inside me lurched. Within seconds, I reached for my phone. I didn’t even have anything urgent to check—just mindless scrolling. Five minutes in, I was already half-sitting up, wondering if I should fold the laundry or answer one last email. Before I knew it, I was back on my feet, tidying up t…
Source https://tinybuddha.com/blog/why-you-cant-relax-and-how-to-let-yourself-rest/
“Rest and be thankful.” ~William Wordsworth
A few years ago, I caught myself doing something that made no sense.
It was late evening, my kids were asleep, the house finally quiet. I’d been counting down to this moment all day—dreaming of sinking into the couch, wrapping myself in a blanket, maybe even reading a book without distractions.
But when I lay down and closed my eyes, something inside me lurched. Within seconds, I reached for my phone. I didn’t even have anything urgent to check—just mindless scrolling. Five minutes in, I was already half-sitting up, wondering if I should fold the laundry or answer one last email. Before I knew it, I was back on my feet, tidying up t…
Source https://seniorplanet.org/articles-sa-laurie-dancing-mental-health/
Sponsored Athlete Laurie shares how dance workouts have dramatically changed her mental health and attitude. Save the date for Zumba with Laurie on Zoom!
The post Laurie, 68 – Dancing Improves Mental Health appeared first on Senior Planet from AARP.
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Source https://seniorplanet.org/articles-sa-laurie-dancing-mental-health/
Sponsored Athlete Laurie shares how dance workouts have dramatically changed her mental health and attitude. Save the date for Zumba with Laurie on Zoom!
The post Laurie, 68 – Dancing Improves Mental Health appeared first on Senior Planet from AARP.
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Source https://www.americanspa.com/resource/pinkini-hard-wax-beads-lycon-gentle-effective-hair-removal
Pinkini Hard Wax Beads by LYCON – Gentle, Effective Hair Removal
Experience silky-smooth results with Pinkini Hard Wax Beads by LYCON. Designed for sensitive areas, this gentle yet powerful formula grips hair—not skin—for a more comfortable waxing experience. Smooth, effective, and trusted by professionals worldwide.
swheeler
Wed, 10/01/2025 – 17:00
Source https://www.americanspa.com/resource/pinkini-hard-wax-beads-lycon-gentle-effective-hair-removal
Pinkini Hard Wax Beads by LYCON – Gentle, Effective Hair Removal
Experience silky-smooth results with Pinkini Hard Wax Beads by LYCON. Designed for sensitive areas, this gentle yet powerful formula grips hair—not skin—for a more comfortable waxing experience. Smooth, effective, and trusted by professionals worldwide.
swheeler
Wed, 10/01/2025 – 17:00
Researchers here offer opinions reflective of the present research mainstream on which mechanisms are important in the aging of the heart and its consequent dysfunctions. This sort of article is an interesting measure of the degree to which the “aging is accumulated damage” viewpoint exemplified by the Strategies for Engineered Negligible Senescence (SENS) has won ground in the ongoing war of ideas regarding the matter of research strategy for the treatment of aging and age-related disease. For example: targeting senescent cells is now mainstream; mitochondrial dysfunction remains a topic in which everyone agrees there is a problem, but disagrees on the nature of that problem; and <a href="https://en.wikipedia.org/w…
Researchers here offer opinions reflective of the present research mainstream on which mechanisms are important in the aging of the heart and its consequent dysfunctions. This sort of article is an interesting measure of the degree to which the “aging is accumulated damage” viewpoint exemplified by the Strategies for Engineered Negligible Senescence (SENS) has won ground in the ongoing war of ideas regarding the matter of research strategy for the treatment of aging and age-related disease. For example: targeting senescent cells is now mainstream; mitochondrial dysfunction remains a topic in which everyone agrees there is a problem, but disagrees on the nature of that problem; and <a href="https://en.wikipedia.org/w…
Tissues in the body are supported by distinct stem cell populations that reside within structures of supporting helper cells known as stem cell niches. The primary purpose of stem cells is to deliver a supply of daughter somatic cells to replace lost cells, though they also provide signaling that affects cell behavior. All tissues undergo a slow turnover of cells as there is a limit to the number of times a somatic cell can replicate. Telomeres are lengths of repeated DNA sequences at the end of chromosomes that shorten with each cell division. When telomeres become too short, a cell reaches wh…
Tissues in the body are supported by distinct stem cell populations that reside within structures of supporting helper cells known as stem cell niches. The primary purpose of stem cells is to deliver a supply of daughter somatic cells to replace lost cells, though they also provide signaling that affects cell behavior. All tissues undergo a slow turnover of cells as there is a limit to the number of times a somatic cell can replicate. Telomeres are lengths of repeated DNA sequences at the end of chromosomes that shorten with each cell division. When telomeres become too short, a cell reaches wh…
Source https://seniorplanet.org/articles-senior-planet-book-club-take-my-hand-by-dolen-perkins-valdez/
Join our book club and enjoy October’s reading selection! View this week’s assignment, and let us know what you think in the comments.
The post Senior Planet Book Club: <em>Take My Hand</em> by Dolen Perkins-Valdez appeared first on Senior Planet from AARP.
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Source https://seniorplanet.org/articles-senior-planet-book-club-take-my-hand-by-dolen-perkins-valdez/
Join our book club and enjoy October’s reading selection! View this week’s assignment, and let us know what you think in the comments.
The post Senior Planet Book Club: <em>Take My Hand</em> by Dolen Perkins-Valdez appeared first on Senior Planet from AARP.
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