Source https://tinybuddha.com/blog/why-ai-can-never-replace-us-the-truth-about-being-human/
“AI accidentally made me believe in the concept of a human soul by showing me what art looks like without it.” ~Unknown
What is intelligence?
I’ve asked this question all my life—as a teacher, a filmmaker, a researcher, and now, as someone losing my vision to macular degeneration.
I ask it when I watch students find their voice.
I ask it when I listen to a close friend of mine, a world-renowned cosmologist, whose knowledge seems limitless but whose humility runs even deeper. He can discuss black holes one minute and quote the Tao Te Ching the next. He doesn’t just know facts—he knows how to listen. He knows how to explain something com…
Source https://tinybuddha.com/blog/why-ai-can-never-replace-us-the-truth-about-being-human/
“AI accidentally made me believe in the concept of a human soul by showing me what art looks like without it.” ~Unknown
What is intelligence?
I’ve asked this question all my life—as a teacher, a filmmaker, a researcher, and now, as someone losing my vision to macular degeneration.
I ask it when I watch students find their voice.
I ask it when I listen to a close friend of mine, a world-renowned cosmologist, whose knowledge seems limitless but whose humility runs even deeper. He can discuss black holes one minute and quote the Tao Te Ching the next. He doesn’t just know facts—he knows how to listen. He knows how to explain something com…
Source https://seniorplanet.org/articles-inspiring-babs-daitch/
Known as “the lesbian Forest Gump,” Babs Daitch (80) has done it all, including starring in her own documentary short.
The post Inspiring Story: Babs Daitch, Documentary Star at 80 appeared first on Senior Planet from AARP.
…
Source https://seniorplanet.org/articles-inspiring-babs-daitch/
Known as “the lesbian Forest Gump,” Babs Daitch (80) has done it all, including starring in her own documentary short.
The post Inspiring Story: Babs Daitch, Documentary Star at 80 appeared first on Senior Planet from AARP.
…
Source https://www.fightaging.org/archives/2025/09/fight-aging-newsletter-september-22nd-2025/
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe to the newsletter,
please visit:
https://www.fightaging.org/newsletter/.
To unsubscribe, send email or reply to this email at newsletter@fightaging.org with “unsubscribe” in the subject or body.
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/
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Source https://www.fightaging.org/archives/2025/09/fight-aging-newsletter-september-22nd-2025/
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe to the newsletter,
please visit:
https://www.fightaging.org/newsletter/.
To unsubscribe, send email or reply to this email at newsletter@fightaging.org with “unsubscribe” in the subject or body.
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/
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Source https://www.fightaging.org/archives/2025/09/short-interspersed-nuclear-elements-expression-as-an-enabler-of-nervous-system-regeneration/
Why does the peripheral nervous system regenerate while the central nervous system does not? Both are composed of clusters of neurons linked by axons that can extend for as much as a few feet in the longest cases. Nerves are bundled axons. One of the approaches taken by researchers interested in applying regenerative medicine strategies to the central nervous system is to look for biochemical differences between peripheral nervous system neurons and axons versus central nervous system neurons and axons. There must exist specific differences that enable regeneration of peripheral nervous system axons or suppress regeneration of central nervous system axons. That doesn’t mean those dif…
Source https://www.fightaging.org/archives/2025/09/short-interspersed-nuclear-elements-expression-as-an-enabler-of-nervous-system-regeneration/
Why does the peripheral nervous system regenerate while the central nervous system does not? Both are composed of clusters of neurons linked by axons that can extend for as much as a few feet in the longest cases. Nerves are bundled axons. One of the approaches taken by researchers interested in applying regenerative medicine strategies to the central nervous system is to look for biochemical differences between peripheral nervous system neurons and axons versus central nervous system neurons and axons. There must exist specific differences that enable regeneration of peripheral nervous system axons or suppress regeneration of central nervous system axons. That doesn’t mean those dif…
Source https://www.fightaging.org/archives/2025/09/failure-to-regulate-diastolic-blood-pressure-as-a-contribution-to-cognitive-decline/
Blood pressure is dynamically regulated in response to circumstances and circadian rhythm. One of the issues arising with age is that this regulation is impaired, such as by the various mechanisms that stiffen blood vessels that include altered behavior of smooth muscle cells and cross-linking of the extracellular matrix. Researchers here show that dysregulation of diastolic blood pressure, in which normal variability is suppressed, can be distinctly correlated to progression of age-related cognitive decline. This is likely a reflection of shared underlying mechanisms that lead to both varied forms of vascular dysfunction in the brain an…
Source https://www.fightaging.org/archives/2025/09/failure-to-regulate-diastolic-blood-pressure-as-a-contribution-to-cognitive-decline/
Blood pressure is dynamically regulated in response to circumstances and circadian rhythm. One of the issues arising with age is that this regulation is impaired, such as by the various mechanisms that stiffen blood vessels that include altered behavior of smooth muscle cells and cross-linking of the extracellular matrix. Researchers here show that dysregulation of diastolic blood pressure, in which normal variability is suppressed, can be distinctly correlated to progression of age-related cognitive decline. This is likely a reflection of shared underlying mechanisms that lead to both varied forms of vascular dysfunction in the brain an…
Source https://www.fightaging.org/archives/2025/09/towards-artificial-elastin-for-tissue-engineering-and-regenerative-medicine/
Elastin is a vital component of flexible tissues, and poorly maintained in the adult body. Deterioration of elastin is an important component of the age-related structural alterations that take place in tissues such as skin and blood vessels. Elastin is also hard to obtain or manufacture for use in engineered tissues, which is the primary roadblock motivating the research noted here. While this is useful, a robust source of elastin (or as here, elastin-like proteins that suitably mimic the behavior of elastin) would probably do relatively little to enable therapies to restore elastin structures in aged tissues, as those elastin structures are complex and the configuration of elastin molecules relative to other components of the <a href="https://en.wikipedia.org/wiki/Extracellular_ma…
Source https://www.fightaging.org/archives/2025/09/towards-artificial-elastin-for-tissue-engineering-and-regenerative-medicine/
Elastin is a vital component of flexible tissues, and poorly maintained in the adult body. Deterioration of elastin is an important component of the age-related structural alterations that take place in tissues such as skin and blood vessels. Elastin is also hard to obtain or manufacture for use in engineered tissues, which is the primary roadblock motivating the research noted here. While this is useful, a robust source of elastin (or as here, elastin-like proteins that suitably mimic the behavior of elastin) would probably do relatively little to enable therapies to restore elastin structures in aged tissues, as those elastin structures are complex and the configuration of elastin molecules relative to other components of the <a href="https://en.wikipedia.org/wiki/Extracellular_ma…
Source https://www.ageinplacetech.com/blog/ai-functionality-there-today-healthcare-home-care-and-long-term-care
Source https://www.ageinplacetech.com/blog/ai-functionality-there-today-healthcare-home-care-and-long-term-care
Source https://www.fightaging.org/archives/2025/09/neural-progenitor-cell-transplantation-promotes-recovery-following-stroke-in-mice/
Researchers here report that human neural progenitor cells derived from induced pluripotent stem cells (iPSCs) can induce some degree of recovery from stroke in mice. As expected for a cell therapy of this nature, functional recovery results from signaling provided by the transplanted cells that favorably alters the behavior of native cells. Inducing regeneration in the brain is important for more than just the damage of stroke, and so is an area of research worth keeping an eye on. In the case of stroke itself, however, more attention should be directed towards prevention: developing means of regressing atherosclerotic plaque to prevent rupture and blockage of vessels in the brain and othe…
Source https://www.fightaging.org/archives/2025/09/neural-progenitor-cell-transplantation-promotes-recovery-following-stroke-in-mice/
Researchers here report that human neural progenitor cells derived from induced pluripotent stem cells (iPSCs) can induce some degree of recovery from stroke in mice. As expected for a cell therapy of this nature, functional recovery results from signaling provided by the transplanted cells that favorably alters the behavior of native cells. Inducing regeneration in the brain is important for more than just the damage of stroke, and so is an area of research worth keeping an eye on. In the case of stroke itself, however, more attention should be directed towards prevention: developing means of regressing atherosclerotic plaque to prevent rupture and blockage of vessels in the brain and othe…
Source https://minimalistbaker.com/gluten-free-pita/
We’ve long admired the super talented gluten-free chef and baker Aran Goyoaga. But our status went from fans to super fans last year when she posted a video of the fluffiest gluten-free dinner rolls we had ever seen. They looked like fluffy, dreamy clouds — how could they possibly be gluten-free?! We wanted to reach through the screen to make sure they were real (translation: eat the whole pan 🤤).
Then earlier this year, Aran announced she was writing a new cookbook(!!) and we nearly started doing cartwheels.
Pillowy Gluten-Free Pita (from Aran GoyoagaR…
Source https://minimalistbaker.com/gluten-free-pita/
We’ve long admired the super talented gluten-free chef and baker Aran Goyoaga. But our status went from fans to super fans last year when she posted a video of the fluffiest gluten-free dinner rolls we had ever seen. They looked like fluffy, dreamy clouds — how could they possibly be gluten-free?! We wanted to reach through the screen to make sure they were real (translation: eat the whole pan 🤤).
Then earlier this year, Aran announced she was writing a new cookbook(!!) and we nearly started doing cartwheels.
Pillowy Gluten-Free Pita (from Aran GoyoagaR…
Source https://www.fightaging.org/archives/2025/09/hippo-pathway-inhibition-provides-resistance-to-ferroptosis-in-the-aging-brain/
The Hippo pathway shows up in many areas of research into aging, regeneration, cancer, and cellular senescence. This tends to be the case for protein machinery that is involved in cell growth and cell stress responses, including programmed cell death. See the research surrounding nutrient signaling and its relationship with cell growth, centering around mTOR and its surrounding biochemistry, for example. Hippo signaling is fairly complex, but also quite well explored. Nonetheless while individual protein interactions in the pathway are well mapped, how it operates in detail to produce different outcomes in different contexts is less well understood. It…
Source https://www.fightaging.org/archives/2025/09/hippo-pathway-inhibition-provides-resistance-to-ferroptosis-in-the-aging-brain/
The Hippo pathway shows up in many areas of research into aging, regeneration, cancer, and cellular senescence. This tends to be the case for protein machinery that is involved in cell growth and cell stress responses, including programmed cell death. See the research surrounding nutrient signaling and its relationship with cell growth, centering around mTOR and its surrounding biochemistry, for example. Hippo signaling is fairly complex, but also quite well explored. Nonetheless while individual protein interactions in the pathway are well mapped, how it operates in detail to produce different outcomes in different contexts is less well understood. It…
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The AI infrastructure juggernaut is on – consumers hesitate and deployment is cautious. Parallel tracks are emerging. Investment by the