Source https://tinybuddha.com/blog/what-if-growth-is-about-removing-not-adding-more-to-your-life/
“Maybe the journey isn’t so much about becoming anything. Maybe it’s about un-becoming everything that isn’t really you, so you can be who you were meant to be in the first place.” ~Paulo Coelho
For years, any time I felt sadness, insecurity, loneliness, or any of those “unwelcome” feelings, I jumped into action.
I’d look for something new to take on: a class, a language, a project, a degree. Once, in the span of a single week, I signed up for language classes, researched getting certified in something I didn’t actually want to do, and convinced myself I needed to start training for a 10K.
Because if I was doing something productive, I wouldn’t have to sit with what I was feeling. Tha…
Reviewing What is Known of Glial Cell Aging in the Cerebellum
The category of glial cells covers all of the supporting cells of the brain, everything not a neuron, a big tent that includes immune cells such as microglia, the oligodendrocytes that manufacture myelin sheathing for axons, and the sizable astrocyte population, among others. These are very different cell populations with very different functions and behaviors, but all become dysfunctional with age. The present consensus is that glial cell dysfunction is important in aging and neurodegenerative conditions, each population contributing to loss of cognitive fun…
The category of glial cells covers all of the supporting cells of the brain, everything not a neuron, a big tent that includes immune cells such as microglia, the oligodendrocytes that manufacture myelin sheathing for axons, and the sizable astrocyte population, among others. These are very different cell populations with very different functions and behaviors, but all become dysfunctional with age. The present consensus is that glial cell dysfunction is important in aging and neurodegenerative conditions, each population contributing to loss of cognitive fun…
The CCND1-CDK6 Complex as a Target for Senotherapeutics
Source https://www.fightaging.org/archives/2025/09/the-ccnd1-cdk6-complex-as-a-target-for-senotherapeutics/
Senescent cells accumulate with age in tissues throughout the body, primarily when a cell reaches the Hayflick limit on replication, but also because of damage or stress. When a cell becomes senescent it ceases to replicate and undergoes profound metabolic changes that cause it to secrete a pro-inflammatory, pro-growth set of signals known as the senescence-associated secretory phenotype (SASP). This serves a useful purpose in the context of potentially cancerous cells, attracting the immune system to destroy them, and aids in regeneration from…
Source https://www.fightaging.org/archives/2025/09/the-ccnd1-cdk6-complex-as-a-target-for-senotherapeutics/
Senescent cells accumulate with age in tissues throughout the body, primarily when a cell reaches the Hayflick limit on replication, but also because of damage or stress. When a cell becomes senescent it ceases to replicate and undergoes profound metabolic changes that cause it to secrete a pro-inflammatory, pro-growth set of signals known as the senescence-associated secretory phenotype (SASP). This serves a useful purpose in the context of potentially cancerous cells, attracting the immune system to destroy them, and aids in regeneration from…
I Wanted Revenge; Here’s Why I Let It Be Instead
Source https://tinybuddha.com/blog/i-wanted-revenge-heres-why-i-let-it-be-instead/
“To let go does not mean to get rid of. To let go means to let be.” ~Jack Kornfield
I must admit right off the bat—as a serial entrepreneur, I’m a risk-taker. Throughout my twenties and thirties, I jumped at opportunities without always vetting the characters involved or asking what six months down the road might look like. I trusted, I leapt, I learned.
At twenty-three, I launched my first real business with another partner—an upscale pet resort. We had climate-controlled suites, a beautiful play yard, and classical music playing softly in the background. An elaborate four-tier fountain greeted guests in the lobby, where you could also view the handcrafted “Catio” patio built by my fath…
Source https://tinybuddha.com/blog/i-wanted-revenge-heres-why-i-let-it-be-instead/
“To let go does not mean to get rid of. To let go means to let be.” ~Jack Kornfield
I must admit right off the bat—as a serial entrepreneur, I’m a risk-taker. Throughout my twenties and thirties, I jumped at opportunities without always vetting the characters involved or asking what six months down the road might look like. I trusted, I leapt, I learned.
At twenty-three, I launched my first real business with another partner—an upscale pet resort. We had climate-controlled suites, a beautiful play yard, and classical music playing softly in the background. An elaborate four-tier fountain greeted guests in the lobby, where you could also view the handcrafted “Catio” patio built by my fath…
Senior Planet Book Club: Vote for Our Next Books!
Source https://seniorplanet.org/senior-planet-book-club-vote-for-our-next-books-oct-and-nov/
Which books should we read next?
The post Senior Planet Book Club: Vote for Our Next Books! appeared first on Senior Planet from AARP.
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Source https://seniorplanet.org/senior-planet-book-club-vote-for-our-next-books-oct-and-nov/
Which books should we read next?
The post Senior Planet Book Club: Vote for Our Next Books! appeared first on Senior Planet from AARP.
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Nate, 71 – “Level Up” with a New Vision of Aging
Source https://seniorplanet.org/articles-sa-nate-71-level-up/
Sponsored Athlete Nate explains how it’s never too late to “level up” your fitness and overall well-being. Get inspired by Nate’s motivational tips, and join him for a virtual workout!
The post Nate, 71 – “Level Up” with a New Vision of Aging appeared first on Senior Planet from AARP.
…
Source https://seniorplanet.org/articles-sa-nate-71-level-up/
Sponsored Athlete Nate explains how it’s never too late to “level up” your fitness and overall well-being. Get inspired by Nate’s motivational tips, and join him for a virtual workout!
The post Nate, 71 – “Level Up” with a New Vision of Aging appeared first on Senior Planet from AARP.
…
Why we’re sponsoring a kids soccer league and what it has to do with fitness
Source https://www.nerdfitness.com/blog/kids-soccer/
My daughter was terrified walking into her first soccer practice. She didn’t know anyone. She wasn’t sure she’d be good enough, or what her teammates would think of her.
But by the end of the hour, she was buzzing with excitement. Thanks to a coach who made sure every kid felt like they belonged, supportive teammates, and lots of positive reinforcement.
That moment reminded me why Nerd Fitness exists.
That spirit – of making everyone feel seen, encouraged, and a part of the team, no matter what their starting point is – is exactly what I think is missing from most of the fitness industry.
Too often, gym and classes feel like competitive sports leagues – designed for people who already love working out, already feel confident, already know what they’re doing.
But what if you’re the “new kid” walking into your first workout at age 30…or 50…or 70? It can feel just as intimidating as my nine…
Source https://www.nerdfitness.com/blog/kids-soccer/
My daughter was terrified walking into her first soccer practice. She didn’t know anyone. She wasn’t sure she’d be good enough, or what her teammates would think of her.
But by the end of the hour, she was buzzing with excitement. Thanks to a coach who made sure every kid felt like they belonged, supportive teammates, and lots of positive reinforcement.
That moment reminded me why Nerd Fitness exists.
That spirit – of making everyone feel seen, encouraged, and a part of the team, no matter what their starting point is – is exactly what I think is missing from most of the fitness industry.
Too often, gym and classes feel like competitive sports leagues – designed for people who already love working out, already feel confident, already know what they’re doing.
But what if you’re the “new kid” walking into your first workout at age 30…or 50…or 70? It can feel just as intimidating as my nine…
Cardiovascular Disease Correlates Robustly with Dementia Risk
Cardiovascular disease correlates very well with incidence of dementia, and this is well demonstrated via analysis of epidemiological data in papers such as the one noted here. Disruption of the flow of blood to the brain is a possible causal mechanism, but one can also consider that both classes of condition are driven by the same underlying processes, such as chronic inflammation. More generally, aspects of aging correlate because aging is an accumulation of damage throughout the body and damaged systems tend to become dysfunctional and fail. The correlation between cardiovascular disease and dementia is strong enough, however, to suggest an additional <a href="https://www.fightaging.org/arc…
Cardiovascular disease correlates very well with incidence of dementia, and this is well demonstrated via analysis of epidemiological data in papers such as the one noted here. Disruption of the flow of blood to the brain is a possible causal mechanism, but one can also consider that both classes of condition are driven by the same underlying processes, such as chronic inflammation. More generally, aspects of aging correlate because aging is an accumulation of damage throughout the body and damaged systems tend to become dysfunctional and fail. The correlation between cardiovascular disease and dementia is strong enough, however, to suggest an additional <a href="https://www.fightaging.org/arc…
If You Wouldn’t Buy It Again, Don’t Keep It
Source https://www.theminimalists.com/oldclothes/
Joshua Fields Millburn discusses what to do with clothes that no longer fit.
What do you do with old clothes that don’t fit anymore? Let us know in the YouTube comments.
The post If You Wouldn’t Buy It Again, Don’t Keep It appeared first on The Minimalists.
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Source https://www.theminimalists.com/oldclothes/
Joshua Fields Millburn discusses what to do with clothes that no longer fit.
What do you do with old clothes that don’t fit anymore? Let us know in the YouTube comments.
The post If You Wouldn’t Buy It Again, Don’t Keep It appeared first on The Minimalists.
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Declines from Peak Cognitive Function Start in Early Adulthood
Cognitive function can be measured in many different ways. It is generally considered to consist of a number of different domains that are influenced by different aspects of brain physiology and biochemistry, and which can improve and decline to different degrees over the course of a lifetime. We should expect the various forms of memory, executive function, sensory processing, and cognitive control to be capable of differing in trajectories as degenerative aging progresses, for example. Indeed, studies show this to be the case. While the story of aging writ large is a story of decline, the details have considerable latitude to vary.
The brain develops, and then the …
Cognitive function can be measured in many different ways. It is generally considered to consist of a number of different domains that are influenced by different aspects of brain physiology and biochemistry, and which can improve and decline to different degrees over the course of a lifetime. We should expect the various forms of memory, executive function, sensory processing, and cognitive control to be capable of differing in trajectories as degenerative aging progresses, for example. Indeed, studies show this to be the case. While the story of aging writ large is a story of decline, the details have considerable latitude to vary.
The brain develops, and then the …