Author: Tom

Source https://www.fightaging.org/archives/2025/08/the-gut-microbiome-contributes-to-the-progression-of-heart-failure/

In recent years, research has indicated that the composition of the gut microbiome is influential on long-term heath and the progression of aging and age-related conditions, perhaps to a similar degree as the better studied influences of weight and exercise. The scientific community has made inroads into correlating specific microbial species and metabolites with specific conditions, and has demonstrated that altering the balance of populations making up the gut microbiome can improve health and extend life in aged animals. Here, researchers review what is known of the ways in which age-related changes in the composition of the gut microbiome can contribute to the progression of heart failure…

Source https://www.fightaging.org/archives/2025/08/the-characteristics-of-age-related-disease-in-very-long-lived-individuals/

Aging is accumulated damage, with age-related disease as the most visible dysfunction that results from that damage. Eventually one of those dysfunctions becomes large enough to cause death. The only way to live longer is to have a lower burden of damage, and thus exhibit lesser degrees of dysfunction. In human populations, this appears to be the case. The study noted here is one of a number to show that centenarians develop fewer and less severe age-related conditions than their peers who fail to live as long. The most interesting observation is that centenarians exhibit a relatively larger incidence of cancer as a fraction of all conditions. One might theorize that this is because their cells are undertaking a greater degree of maintenance activities in the age-damaged tissue environment. Cancer is a numbers game, and the more <a href="https://en.wikipedia.org/wik…

Source https://www.fightaging.org/archives/2025/08/reviewing-the-state-of-clinical-evidence-for-rapamycin-as-an-age-slowing-treatment/

From a starting point of the small list of options to treat aging that are presently accessible to the average individual, if pushed to list the interventions with the most useful human evidence for safety, the most robust and replicated animal data for efficacy, and with relatively well-explored mechanisms of action, then one might start with (a) calorie restriction, (b) exercise, (c) rapamycin, and then (d) the senolytic combination of dasatinib and quercetin. Note that I say nothing of effect sizes when…

Source https://seniorplanet.org/articles-sa-steven-72-bodyweight-isometric-exercise/

Sponsored Athlete Steven shares the benefits of bodyweight exercises for beginners and road warriors alike, and invites you to join him for an equipment-free workout.

The post Steven, 72 – Staying Strong Anywhere: The Power of Bodyweight and Isometric Exercises appeared first on Senior Planet from AARP.

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Source https://www.fightaging.org/archives/2025/08/fat-tissue-contributes-to-the-production-of-a-population-of-age-associated-t-cells/

The immune system ages in complex ways, but the result of all of this complexity is chronic inflammation and incapacity, the states of inflammaging and immunosenescence. An aged immune system causes tissue dysfunction on the one hand, while failing to protect against infectious pathogens and malfunctioning cells on the other hand. Focused on one specific part of this big picture, researchers here explore the origins of a dysfunctional population of T cells that emerges in later life to contribute to overall immune dysfunction. They find that fat tissue appears important in encouraging this population to expand from its <a href="https://en.wikipedia…

Source https://www.theminimalists.com/sustainable/

The Minimalists discuss ten ways to go green and save money.

What’s your favorite way to be eco-friendly on a budget? Let us know in the YouTube comments.

The post The 10 most sustainable products… appeared first on The Minimalists.

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Source https://www.fightaging.org/archives/2025/08/in-search-of-antagonistic-pleiotropy-in-human-data/

Antagonistic pleiotropy is a term used to describe a biological mechanism that is helpful in one context, harmful in another. As most often used, this means helpful when young, harmful when old. The concept of antagonistic pleiotropy sits at the heart of any serious discussion of the evolution of aging, as well as the relationships between known mechanisms of aging and hallmarks of aging. The dominant view of aging is that it is a side-effect of natural selection operating more strongly on the characteristics of young individuals than on the characteristics of old individuals, favoring the evolution of mechanisms that enhance early survival and reproductive succe…

Source https://www.ageinplacetech.com/blog/how-do-caregivers-learn-about-tech-they-could-use

Source https://seniorplanet.org/articles-tech-hub-al-update/

Tech Hub, Senior Planet’s new monthly feature, will help you keep up with the rapid pace of tech innovations. This month we explore AI..

The post Tech Hub Debut: Al Update appeared first on Senior Planet from AARP.

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Source https://tinybuddha.com/blog/the-child-i-lost-and-the-inner-child-im-now-learning-to-love/

“Our sorrows and wounds are healed only when we touch them with compassion.” ~Jack Kornfield

Her absence lingers in the stillness of early mornings, in the moments between tasks, in the hush of evening when the day exhales. I’ve gotten good at moving. At staying busy. At producing. But sometimes, especially lately, the quiet catches me—and I fall in.

Grief doesn’t always roar. Sometimes it’s a whisper, one you barely hear until it’s grown into a wind that bends your bones.

It’s been nearly three years since my daughter passed. People told me time would help. That the firsts—first holidays, first birthday without her—would be the hardest. And maybe that was true.

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