Sepsis is a state of runaway inflammation in response to infection, a condition that is more serious and more often fatal in older individuals. With age, the immune system becomes every more overactive and inflammatory, reacting to signals created by the damaged environment of the body. This background of chronic inflammation makes it ever less likely that any given incident of greatly raised inflammatory signaling will successfully resolve. Instead inflammation can rage to the point of causing serious harm and organ failure.
At present, treatments for sepsis are largely palliative, or focus on <a href="https://www.fightaging.org/archives/2014/10/a-device-to-clear-pathogens-from-blood-to…
Sepsis is a state of runaway inflammation in response to infection, a condition that is more serious and more often fatal in older individuals. With age, the immune system becomes every more overactive and inflammatory, reacting to signals created by the damaged environment of the body. This background of chronic inflammation makes it ever less likely that any given incident of greatly raised inflammatory signaling will successfully resolve. Instead inflammation can rage to the point of causing serious harm and organ failure.
At present, treatments for sepsis are largely palliative, or focus on <a href="https://www.fightaging.org/archives/2014/10/a-device-to-clear-pathogens-from-blood-to…
Age-related frailty is accompanied by marked chronic inflammation, and indeed much of the physical weakness of frailty is likely caused by long-term inflammation and the ways in which it disrupts muscle tissue maintenance. The tools presently available to suppress inflammation are somewhat blunt, interfering in the necessary signaling needed to maintain a normal immune response, as well as in the unwanted overactivation of the immune system found in older people. Nonetheless, such tools are slowly becoming better and more selective over time, and some are now being tested as treatments for frailty.
Earlier this year, MyMD Pharmaceuticals merged with <a href="https://www.akersbioscience…
Age-related frailty is accompanied by marked chronic inflammation, and indeed much of the physical weakness of frailty is likely caused by long-term inflammation and the ways in which it disrupts muscle tissue maintenance. The tools presently available to suppress inflammation are somewhat blunt, interfering in the necessary signaling needed to maintain a normal immune response, as well as in the unwanted overactivation of the immune system found in older people. Nonetheless, such tools are slowly becoming better and more selective over time, and some are now being tested as treatments for frailty.
Earlier this year, MyMD Pharmaceuticals merged with <a href="https://www.akersbioscience…
Protein is the darling of the macro world (sorry, fat and carbs), and protein powder is one of the most convenient ways to get an extra dose of it — whether you’re trying to lose fat, gain muscle, or both.
But you may be wondering if women have different protein powder needs than men, or if any protein powder provides certain advantages to women specifically. (Spoiler alert: Nah.)
So, grab that BlenderBottle and get ready to shake it like a salt shaker, ’cause here are the best protein powders for women (and everyone else too).
Protein is the darling of the macro world (sorry, fat and carbs), and protein powder is one of the most convenient ways to get an extra dose of it — whether you’re trying to lose fat, gain muscle, or both.
But you may be wondering if women have different protein powder needs than men, or if any protein powder provides certain advantages to women specifically. (Spoiler alert: Nah.)
So, grab that BlenderBottle and get ready to shake it like a salt shaker, ’cause here are the best protein powders for women (and everyone else too).
If you’ve ever heard anything about milk thistle — a prickly plant named for the white veins on its leaves — it might be that it can help your liver detox after a big night of boozing. Widely available as a supplement, you can get it as a powder, in capsules, or as an extract.
In fact, milk thistle has long been used as a natural remedy to support liver health and claims abound for the other ways the plant could give your body a boost. Why? Milk thistle contains the compound silymarin, a flavonoid thought to have antioxidant properties.
Let’s take a look at the science behind these claims to see if there’s reason enough to boost your confidence in this supplement.
<img loading="lazy" width="1296" height="728" src="https://post.greatist.com/wp-content/uploads/sites/2/2020/06/173184-grt-Why-Milk-Thistle-Is-Great-for-Your-Body-1296×728-Header.jpg" alt="benefits of milk thistle" class="wp-image-178355…
If you’ve ever heard anything about milk thistle — a prickly plant named for the white veins on its leaves — it might be that it can help your liver detox after a big night of boozing. Widely available as a supplement, you can get it as a powder, in capsules, or as an extract.
In fact, milk thistle has long been used as a natural remedy to support liver health and claims abound for the other ways the plant could give your body a boost. Why? Milk thistle contains the compound silymarin, a flavonoid thought to have antioxidant properties.
Let’s take a look at the science behind these claims to see if there’s reason enough to boost your confidence in this supplement.
<img loading="lazy" width="1296" height="728" src="https://post.greatist.com/wp-content/uploads/sites/2/2020/06/173184-grt-Why-Milk-Thistle-Is-Great-for-Your-Body-1296×728-Header.jpg" alt="benefits of milk thistle" class="wp-image-178355…
We had BIG dreams for a vegan, gluten-free version of classic white chocolate macadamia nut cookies. Little did we know, good vegan white chocolate chips are hard to come by! But when we swapped them for dried cranberries in this new dough, we found our new favorite cookie!
These cookies taste just like the classics — they’re soft, sweet, vanilla-infused, and we’re confident you won’t even miss the chocolate!
We had BIG dreams for a vegan, gluten-free version of classic white chocolate macadamia nut cookies. Little did we know, good vegan white chocolate chips are hard to come by! But when we swapped them for dried cranberries in this new dough, we found our new favorite cookie!
These cookies taste just like the classics — they’re soft, sweet, vanilla-infused, and we’re confident you won’t even miss the chocolate!
It is widely appreciated in the research community that the general age-related decline in mitochondrial function (and in mitophagy, the quality control mechanism responsible for culling broken mitochondria) is important to the progression of degenerative aging and onset of age-related disease. A great many research groups are looking into ways to boost mitophagy and mitochondrial function, some purely compensatory and unrelated to age-related changes, while others attempt to address some part of the poorly mapped chain of cause and consequence that leads from the <a href="https://www.fightaging.org/faq/#causes-…
It is widely appreciated in the research community that the general age-related decline in mitochondrial function (and in mitophagy, the quality control mechanism responsible for culling broken mitochondria) is important to the progression of degenerative aging and onset of age-related disease. A great many research groups are looking into ways to boost mitophagy and mitochondrial function, some purely compensatory and unrelated to age-related changes, while others attempt to address some part of the poorly mapped chain of cause and consequence that leads from the <a href="https://www.fightaging.org/faq/#causes-…
Autophagy is a collection of processes that remove damaged and unwanted molecules and structures from a cell, delivering them to a lysosome where they are broken down into raw materials for further protein synthesis. Many of the approaches shown to slow aging in short-lived species are characterized by improved autophagy, and evidence from research into calorie restriction suggests that autophagy may be the most important of the many mechanisms linking the operation of cellular metabolism to the pace of aging. <a href="https://www.fightaging.org/archives/2021/09/restoration-of-autoph…
Autophagy is a collection of processes that remove damaged and unwanted molecules and structures from a cell, delivering them to a lysosome where they are broken down into raw materials for further protein synthesis. Many of the approaches shown to slow aging in short-lived species are characterized by improved autophagy, and evidence from research into calorie restriction suggests that autophagy may be the most important of the many mechanisms linking the operation of cellular metabolism to the pace of aging. <a href="https://www.fightaging.org/archives/2021/09/restoration-of-autoph…
If there’s one group of people that cares deeply about socks, it’s runners. Wearing the right socks when you run is a BFD. In case you’re scoping out a new pair of running socks, we’ve assembled all our faves in a wide variety of styles and cuts right here.
And if you’re new to running and not on the sock-hype train yet, you’re about to learn more than you ever thought you needed to know about socks.
If there’s one group of people that cares deeply about socks, it’s runners. Wearing the right socks when you run is a BFD. In case you’re scoping out a new pair of running socks, we’ve assembled all our faves in a wide variety of styles and cuts right here.
And if you’re new to running and not on the sock-hype train yet, you’re about to learn more than you ever thought you needed to know about socks.
