Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit: https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/
Contents
Dysregulated Oxalate Metabolism in Macrophages in Atherosclerosis
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit: https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out more: https://www.fightaging.org/services/
Contents
Dysregulated Oxalate Metabolism in Macrophages in Atherosclerosis
Often when our lives have a bunch of things going on at once, and multiple things to manage in each of those areas … it can feel really messy and scattered.
This kind of feeling of messiness can cause us stress, and make us unhappy with our current situation.
We might feel like we’re doing things wrong. We might feel like we’re trying to keep our heads above water, and struggling with it. We might feel helpless, like there’s not much we can do about it.
If you feel scattered like this … I’m here to say that this is a very common feeling, and you’re not alone. Many of us feel scattered, overwhelmed, like our lives are messy and out of control.
There are some tactical things we can do to feel more under control … and there’s a mindset shift (or practice) we can do to get good at feeli…
Often when our lives have a bunch of things going on at once, and multiple things to manage in each of those areas … it can feel really messy and scattered.
This kind of feeling of messiness can cause us stress, and make us unhappy with our current situation.
We might feel like we’re doing things wrong. We might feel like we’re trying to keep our heads above water, and struggling with it. We might feel helpless, like there’s not much we can do about it.
If you feel scattered like this … I’m here to say that this is a very common feeling, and you’re not alone. Many of us feel scattered, overwhelmed, like our lives are messy and out of control.
There are some tactical things we can do to feel more under control … and there’s a mindset shift (or practice) we can do to get good at feeli…
Yes, your genetics can contribute to migraine. While scientists have found it pretty tricky to understand how it all works, they know that your genes play a big ol’ role in whether you have migraine.
Is migraine hereditary?
Yes, it can be.
Experts don’t fully understand why some people inherit migraine and others don’t. Scientists don’t agree on how much genetics contributes to migraine, but Genetics Home Reference estimates that more than half of those living with migraine have someone else in their family with the condition.
The causes of migraine are complex, involving a combination of genetics, environment, and lifestyle factors.
While estimates vary depending on the source, your genes may contribute <a href…
Yes, your genetics can contribute to migraine. While scientists have found it pretty tricky to understand how it all works, they know that your genes play a big ol’ role in whether you have migraine.
Is migraine hereditary?
Yes, it can be.
Experts don’t fully understand why some people inherit migraine and others don’t. Scientists don’t agree on how much genetics contributes to migraine, but Genetics Home Reference estimates that more than half of those living with migraine have someone else in their family with the condition.
The causes of migraine are complex, involving a combination of genetics, environment, and lifestyle factors.
While estimates vary depending on the source, your genes may contribute <a href…
Vitamins and minerals are micronutrients. And, without them, our bodies wouldn’t develop or function correctly.
From helping you turn food into fuel to fortifying bones and eyesight, vitamins and minerals are the Beyoncé of the health world — they’re extremely capable, everything revolves around them, and they have powerful effects on their environment.
We see cartons of juice and boxes of cereal trumpeting their vitamin and mineral content, but what are these microscopic nutrients, really? What do they do? How do they work? And why are they so important?
Vitamins and minerals are micronutrients. And, without them, our bodies wouldn’t develop or function correctly.
From helping you turn food into fuel to fortifying bones and eyesight, vitamins and minerals are the Beyoncé of the health world — they’re extremely capable, everything revolves around them, and they have powerful effects on their environment.
We see cartons of juice and boxes of cereal trumpeting their vitamin and mineral content, but what are these microscopic nutrients, really? What do they do? How do they work? And why are they so important?
“If there is no struggle, there is no progress.” ~Frederick Douglass
In an eighteen-month window, I had a landslide of firsts that I would not wish on my worst enemy.
I ended my first long-term relationship with someone I deeply cared for but did not love. She had borderline personality disorder, and I was not mentally strong enough nor mature enough to be what she needed in a partner. Within five minutes of me saying our relationship was over, she slit her wrist as we sat there in bed. This was the beginning of it all.
Drug overdoses, online personal attacks, physically beating me, calling and texting sixty-plus times a day, coming to my work, breaking into my home to steal and trash the place, and general emotional …
“If there is no struggle, there is no progress.” ~Frederick Douglass
In an eighteen-month window, I had a landslide of firsts that I would not wish on my worst enemy.
I ended my first long-term relationship with someone I deeply cared for but did not love. She had borderline personality disorder, and I was not mentally strong enough nor mature enough to be what she needed in a partner. Within five minutes of me saying our relationship was over, she slit her wrist as we sat there in bed. This was the beginning of it all.
Drug overdoses, online personal attacks, physically beating me, calling and texting sixty-plus times a day, coming to my work, breaking into my home to steal and trash the place, and general emotional …
In a quiet room, we can find stillness. And in that stillness, we can contemplate our own mind.
What we often find is that the mind is very restless. It wants to take care of a thousand things, because it’s feeling some uncertainty and fear. It wants to fix problems, take care of all the undone things, figure out if everything is going to be OK. It wants to get all of our needs met, from survival needs to meaning, connection and love.
The mind is restless, wanting to fix everything, get everything it needs.
What if we could allow our minds to rest, settling into the full sufficiency of itself just as it is?
We would need nothing in each moment, other than what’s required for physical survival. That doesn’t mean we do nothing (though we could!) — beyond our needs, there might be a wholehearted desire to do some good for ourselves or others, but it doesn’t …
In a quiet room, we can find stillness. And in that stillness, we can contemplate our own mind.
What we often find is that the mind is very restless. It wants to take care of a thousand things, because it’s feeling some uncertainty and fear. It wants to fix problems, take care of all the undone things, figure out if everything is going to be OK. It wants to get all of our needs met, from survival needs to meaning, connection and love.
The mind is restless, wanting to fix everything, get everything it needs.
What if we could allow our minds to rest, settling into the full sufficiency of itself just as it is?
We would need nothing in each moment, other than what’s required for physical survival. That doesn’t mean we do nothing (though we could!) — beyond our needs, there might be a wholehearted desire to do some good for ourselves or others, but it doesn’t …
Oh, sh*t! you completely forgot to put the cheese back in the fridge before you left for lunch with your bezzies. But do you really have to throw it away? How long can cheese sit out, anyway?
How long can cheese sit out?
Honestly, it just depends on the type of cheese we’re talking about.
The U.S. Department of Health doesn’t recommend keeping any perishable food sitting out of the fridge for more than 2 hours — and that’s definitely the case for soft cheeses, like cottage or cream cheese, brie, or fresh mozzarella. If it’s squishy and it’s been out for 2 or more hours, yeet that sucker into the trash.
Hard cheeses, such as cheddar, Parmesan, or Gouda, are a tougher breed. If they…
Oh, sh*t! you completely forgot to put the cheese back in the fridge before you left for lunch with your bezzies. But do you really have to throw it away? How long can cheese sit out, anyway?
How long can cheese sit out?
Honestly, it just depends on the type of cheese we’re talking about.
The U.S. Department of Health doesn’t recommend keeping any perishable food sitting out of the fridge for more than 2 hours — and that’s definitely the case for soft cheeses, like cottage or cream cheese, brie, or fresh mozzarella. If it’s squishy and it’s been out for 2 or more hours, yeet that sucker into the trash.
Hard cheeses, such as cheddar, Parmesan, or Gouda, are a tougher breed. If they…
There are at present many programs of medical research and development focused on senescent cells: selectively destroying them, suppressing their inflammatory secretions, or preventing cells from becoming senescent in the first place. The accumulation of senescent cells is an important contribution to degenerative aging, and senolytic treatments that clear a sizable fraction of such cells produce <a href="https://www.fightaging.org/archives/2018/07/senolytics-reduce-age-related-dysfunction-and-extend-remaining-life-span-by-36-following-administratio…
There are at present many programs of medical research and development focused on senescent cells: selectively destroying them, suppressing their inflammatory secretions, or preventing cells from becoming senescent in the first place. The accumulation of senescent cells is an important contribution to degenerative aging, and senolytic treatments that clear a sizable fraction of such cells produce <a href="https://www.fightaging.org/archives/2018/07/senolytics-reduce-age-related-dysfunction-and-extend-remaining-life-span-by-36-following-administratio…
It’s a slog searching for data about tech adoption of older adults. So many years of searching and trying to understand gaps in adoption, less and less usable data. Survey organizations exist that track adoption by age (think Pew Research, Nielsen, AARP) – but the frequency of which they publish surveys about technology has diminished over the years. Checking out the main page of Pew, for example. See how so many other topics are more click-worthy than their Internet and Technology material. AARP’s tech surveys are annual – and this year <a href="h…
It’s a slog searching for data about tech adoption of older adults. So many years of searching and trying to understand gaps in adoption, less and less usable data. Survey organizations exist that track adoption by age (think Pew Research, Nielsen, AARP) – but the frequency of which they publish surveys about technology has diminished over the years. Checking out the main page of Pew, for example. See how so many other topics are more click-worthy than their Internet and Technology material. AARP’s tech surveys are annual – and this year <a href="h…
<figca…
It’s a slog searching for data about tech adoption of older adults. So many years of searching and trying to understand gaps in adoption, less and less usable data. Survey organizations exist that track adoption by age (think Pew Research, Nielsen, AARP) – but the frequency of which they publish surveys about technology has diminished over the years. Checking out the main page of