Source: http://brainblogger.com/2016/04/12/dementia-and-proton-pump-inhibitors-cause-and-effect-or-no-cause-for-concern/
Many older adults take proton pump inhibitors (PPIs) to treat gastrointestinal diseases. And, many older adults have dementia. Recently, a study in JAMA Neurology linked these two common features of the elderly, but questions remain about the validity of the results and about the real risk of PPI use.
The authors of the current study examined eight years of German data and evaluated associations between PPI use and new diagnoses of dementia. They report that the nearly 3,000 people who were older than 75 and regularly used PPIs had a significantly increased risk of developing dementia compared to people who did not regularly use PPIs. (The same group published a similar report of a longitudinal multicenter study in the European Archives of Psychiatry and Clinical Neuroscience; both studies reported an approximately 1.4-fold increased risk of deve…
Source: http://brainblogger.com/2016/04/12/dementia-and-proton-pump-inhibitors-cause-and-effect-or-no-cause-for-concern/
Many older adults take proton pump inhibitors (PPIs) to treat gastrointestinal diseases. And, many older adults have dementia. Recently, a study in JAMA Neurology linked these two common features of the elderly, but questions remain about the validity of the results and about the real risk of PPI use.
The authors of the current study examined eight years of German data and evaluated associations between PPI use and new diagnoses of dementia. They report that the nearly 3,000 people who were older than 75 and regularly used PPIs had a significantly increased risk of developing dementia compared to people who did not regularly use PPIs. (The same group published a similar report of a longitudinal multicenter study in the European Archives of Psychiatry and Clinical Neuroscience; both studies reported an approximately 1.4-fold increased risk of deve…
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