Genetics Behind Response to Parkinson’s Drugs

Source: http://brainblogger.com/2016/08/30/genetics-behind-response-to-parkinsons-drugs/

Since achieving the goals of the “mission impossible” Human Genome Project in 2003, biomedical sciences entered the new era of genetically informed use of pharmaceuticals. The Project helped in our understanding of how genes affect an individual’s response to drugs.

Although it was known for decades that the response to drugs depends on genetic background of each individual, the knowledge of key mechanisms involved in these processes was mostly missing. Genetics finally provided a definite understanding of pharmacokinetics, the branch of science studying what the body does to the drugs. This article will look at how drug response may vary between individuals, and how genetics play an important role in the drug response in patients with Parkinson’s disease.

Why drug responses vary

In general, there are three main reasons why response to …

Source: http://brainblogger.com/2016/08/30/genetics-behind-response-to-parkinsons-drugs/

Since achieving the goals of the “mission impossible” Human Genome Project in 2003, biomedical sciences entered the new era of genetically informed use of pharmaceuticals. The Project helped in our understanding of how genes affect an individual’s response to drugs.

Although it was known for decades that the response to drugs depends on genetic background of each individual, the knowledge of key mechanisms involved in these processes was mostly missing. Genetics finally provided a definite understanding of pharmacokinetics, the branch of science studying what the body does to the drugs. This article will look at how drug response may vary between individuals, and how genetics play an important role in the drug response in patients with Parkinson’s disease.

Why drug responses vary

In general, there are three main reasons why response to …

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