Glioblastoma – Can Gene Therapy Really Help?

Source: http://brainblogger.com/2016/06/14/glioblastoma-can-gene-therapy-really-help/

Glioblastoma is one of the deadliest tumours, with very low survival rate and no efficient therapies available. The current gold standards of management, namely surgery, chemo- and radiotherapy, have little effectiveness since these tumours typically exhibit very aggressive recurrences within a short time frame. In spite of concerted international efforts over the past few decades, an effective treatment for these tumours has remained elusive.

It is sad but true that a diagnosis of glioblastoma is almost equivalent to a death sentence, and most patients who have been diagnosed with a WHO grade IV malignant glioma survive only about 12 months. Although new molecular pathways involved in glioblastoma invasiveness are constantly being uncovered, translation of basic science research into clinical applications has been slow. Additionally, despite advances in tr…

Source: http://brainblogger.com/2016/06/14/glioblastoma-can-gene-therapy-really-help/

Glioblastoma is one of the deadliest tumours, with very low survival rate and no efficient therapies available. The current gold standards of management, namely surgery, chemo- and radiotherapy, have little effectiveness since these tumours typically exhibit very aggressive recurrences within a short time frame. In spite of concerted international efforts over the past few decades, an effective treatment for these tumours has remained elusive.

It is sad but true that a diagnosis of glioblastoma is almost equivalent to a death sentence, and most patients who have been diagnosed with a WHO grade IV malignant glioma survive only about 12 months. Although new molecular pathways involved in glioblastoma invasiveness are constantly being uncovered, translation of basic science research into clinical applications has been slow. Additionally, despite advances in tr…

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