Source: http://brainblogger.com/2016/05/23/how-lsd-changes-the-way-our-brains-work/
In 1938, Swiss chemist Albert Hofmann synthesized a derivative of alkaloid ergotamine, a natural compound found in a parasitic fungus called ergot. He had no way of knowing that as little as 20 micrograms of this substance would cause a psychedelic effect!
Back in the first half of the 20th century, there were not many methods to characterize new chemical compounds, let alone to establish the structure of complex natural substances such as alkaloids. Doing a bit of self-experimentation in the form of examining the smell and test of newly synthesized chemicals was a well-established and routine practice. In fact, many scientific journals of that period reported, among other things, the smell and taste of new compounds. So it doesn’t come as a surprise that Albert Hofmann decided to taste a new compound, which he called LSD-25 (Lysergic acid diethylamide derivative 25), and put a tiny crystal on his tongue.
Since then, <a href="http://brainblogger.com/2015/…
Source: http://brainblogger.com/2016/05/23/how-lsd-changes-the-way-our-brains-work/
In 1938, Swiss chemist Albert Hofmann synthesized a derivative of alkaloid ergotamine, a natural compound found in a parasitic fungus called ergot. He had no way of knowing that as little as 20 micrograms of this substance would cause a psychedelic effect!
Back in the first half of the 20th century, there were not many methods to characterize new chemical compounds, let alone to establish the structure of complex natural substances such as alkaloids. Doing a bit of self-experimentation in the form of examining the smell and test of newly synthesized chemicals was a well-established and routine practice. In fact, many scientific journals of that period reported, among other things, the smell and taste of new compounds. So it doesn’t come as a surprise that Albert Hofmann decided to taste a new compound, which he called LSD-25 (Lysergic acid diethylamide derivative 25), and put a tiny crystal on his tongue.
Since then, <a href="http://brainblogger.com/2015/…
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