A Discussion of Mesenchymal Stem Cell Therapy as a Way to Suppress Age-Related Inflammation

Source https://www.fightaging.org/archives/2021/06/a-discussion-of-mesenchymal-stem-cell-therapy-as-a-way-to-suppress-age-related-inflammation/

First generation mesenchymal stem cell therapies have been shown over the years to fairly reliably suppress chronic inflammation for some time, whether disease-associated or aging-associated. The transplanted cells die quickly, but the effects of their brief burst of signaling can last for months. Other intended benefits, such as increased regeneration or function, are in comparison unreliable at best. In part the challenge is that there is no standard in this part of the field, every clinic uses different methodologies and cell sources. These differences appear to matter greatly, and the fine details of why they matter greatly remain poorly cataloged and poorly understood.

Mese…

Source https://www.fightaging.org/archives/2021/06/a-discussion-of-mesenchymal-stem-cell-therapy-as-a-way-to-suppress-age-related-inflammation/

First generation mesenchymal stem cell therapies have been shown over the years to fairly reliably suppress chronic inflammation for some time, whether disease-associated or aging-associated. The transplanted cells die quickly, but the effects of their brief burst of signaling can last for months. Other intended benefits, such as increased regeneration or function, are in comparison unreliable at best. In part the challenge is that there is no standard in this part of the field, every clinic uses different methodologies and cell sources. These differences appear to matter greatly, and the fine details of why they matter greatly remain poorly cataloged and poorly understood.

Mese…

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