Source https://www.fightaging.org/archives/2025/07/age-related-loss-of-selenoprotein-p-in-macrophages-impairs-muscle-regeneration/
Aging negatively impacts muscle regeneration for reasons that remain incompletely understood. This incomplete understanding exists in part because muscle regeneration involves a complex set of interactions between different cell types that shifts over time as the response to injury progresses. It requires a great deal of effort to build a clear picture at the level of cell biochemistry. Nonetheless, it is evidently the case that aging impairs the activity of muscle stem cells, it impairs the niches in which those cells reside, it alters the behavior of immune cells for the worse, and so forth. There are starting points.
Similarly, one can point to the chronic inflammation of aging and its ability to impairs regeneration, interfering …
Source https://www.fightaging.org/archives/2025/07/age-related-loss-of-selenoprotein-p-in-macrophages-impairs-muscle-regeneration/
Aging negatively impacts muscle regeneration for reasons that remain incompletely understood. This incomplete understanding exists in part because muscle regeneration involves a complex set of interactions between different cell types that shifts over time as the response to injury progresses. It requires a great deal of effort to build a clear picture at the level of cell biochemistry. Nonetheless, it is evidently the case that aging impairs the activity of muscle stem cells, it impairs the niches in which those cells reside, it alters the behavior of immune cells for the worse, and so forth. There are starting points.
Similarly, one can point to the chronic inflammation of aging and its ability to impairs regeneration, interfering …
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